Evidence map›Paper›PMID 29691446›Full record

ArticleScientific reports2018

Morphological parameters and anatomical locations associated with rupture status of small intracranial aneurysms.

Zhihui Duan, Yuanhui Li, Sheng Guan, Congmin Ma, Yuezhen Han, Xiangyang Ren, Liping Wei, Wenbo Li, Jiyu Lou, Zhiyuan Yang

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 88 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Zhihui DuanDepartment of Neurology, Affiliated Luoyang Central Hospital of Zhengzhou University, Luoyang, Henan, P.R. China.
Yuanhui LiDepartment of Interventional Neuroradiology, Affiliated Luoyang Central Hospital of Zhengzhou University, Luoyang, Henan, P.R. China.
Sheng GuanDepartment of Interventional Neuroradiology, The 1st Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, P.R. China.
Congmin MaDepartment of Neurology, Affiliated Luoyang Central Hospital of Zhengzhou University, Luoyang, Henan, P.R. China.
Yuezhen HanDepartment of Neurology, Affiliated Luoyang Central Hospital of Zhengzhou University, Luoyang, Henan, P.R. China.
Xiangyang RenDepartment of Neurology, Affiliated Luoyang Central Hospital of Zhengzhou University, Luoyang, Henan, P.R. China.
Liping WeiDepartment of Interventional Neuroradiology, Affiliated Luoyang Central Hospital of Zhengzhou University, Luoyang, Henan, P.R. China.
Wenbo LiDepartment of Interventional Neuroradiology, Affiliated Luoyang Central Hospital of Zhengzhou University, Luoyang, Henan, P.R. China.
Jiyu LouDepartment of Neurology, The 2nd Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, P.R. China. jiyulou123@126.com.
Zhiyuan YangDepartment of Neurology, Affiliated Luoyang Central Hospital of Zhengzhou University, Luoyang, Henan, P.R. China. yzy0218@126.com.
Luoyang Central Hospital Affiliated to Zhengzhou University · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Characterization of the rupture risk factors for small intracranial aneurysms (SIAs, ≤5 mm) is clinically valuable. The present study aims to identify image-based morphological parameters and anatomical locations associated with the rupture status of SIAs. Two hundred and sixty-three patients with single SIAs (128 ruptured, 135 unruptured) were included, and six morphological parameters, including size, aspect ratio (AR), size ratio (SR), height-width ratio (H/W), flow angle (FA) and aneurysm width-parent artery diameter ratio, and the aneurysm locations were evaluated using three-dimensional geometry, and were used to identify a correlation with aneurysm rupture. Statistically significant differences were observed between ruptured and unruptured groups for AR, SR, H/W, FA, and aneurysm locations, from univariate analyses. Logistic regression analysis further revealed that AR (p = 0.034), SR (p = 0.004), H/W (p = 0.003), and FA (p < 0.001) had the strongest independent correlation with ruptured SIAs after adjustment for age, gender and other clinical risk factors. A future study on a larger SIA cohort need to establish to what extent the AR, SR, H/W and FA increase the risk of rupture in patients with unruptured SIAs in terms of absolute risks.

Indexed as

AgedAneurysm, RupturedCerebral AngiographyCohort StudiesFemaleHumansIntracranial AneurysmMaleMiddle AgedRetrospective StudiesRisk FactorsRupture, Spontaneous

Identifiers

PMID29691446
PMCPMC5915554
OpenAlexW2805483630

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.