Evidence map›Paper›PMID 29691339›Full record

ArticlemBio2018

Outbreak of Invasive Wound Mucormycosis in a Burn Unit Due to Multiple Strains of Mucor circinelloides f. circinelloides Resolved by Whole-Genome Sequencing.

Dea Garcia-Hermoso, Alexis Criscuolo, Soo Chan Lee, Matthieu Legrand, Marc Chaouat, Blandine Denis, Matthieu Lafaurie, Martine Rouveau, Charles Soler, Jean-Vivien Schaal and 7 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. The Yeast in the Vial: IatrogenicJournal of fungi (Basel, Switzerland) · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Molecular mechanisms that govern infection and antifungal resistance in Mucorales.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  9. Review
  10. Review
  11. [Research progress of mucormycosis in burns].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023
    Review
  12. Whole-genome sequencing rule-out of suspected hospital-onsetInfection control and hospital epidemiology · 2023
    Article
  13. Review
  14. Article
  15. Review
  16. Whole genome analysis ofFrontiers in cellular and infection microbiology · 2023
    Article
  17. Article
  18. Two Cases of Post-Traumatic Mucormycosis due toCase reports in infectious diseases · 2022
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 2 countries.

Dea Garcia-Hermoso *Institut Pasteur, National Reference Center for Invasive Mycoses and Antifungals (NRCMA), Molecular Mycology Unit, Paris, France.
Alexis Criscuolo *Institut Pasteur-Bioinformatics and Biostatistics Hub-C3BI, USR 3756 IP CNRS-Paris, France.
Soo Chan LeeSouth Texas Center for Emerging Infectious Diseases (STCEID), Department of Biology, the University of Texas at San Antonio, San Antonio, Texas, USA.
Matthieu LegrandUMR 942, INSERM, Service d'Anesthésie-Réanimation, Assistance Publique-Hôpitaux de Paris (AP-HP), Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Paris, France.
Marc ChaouatUniversité Paris Diderot, Sorbonne Paris Cité, Paris, France.
Blandine DenisService de Maladies Infectieuses et Tropicales, Assistance Publique-Hôpitaux de Paris (AP-HP), Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Paris, France.
Matthieu LafaurieService de Maladies Infectieuses et Tropicales, Assistance Publique-Hôpitaux de Paris (AP-HP), Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Paris, France.
Martine RouveauLaboratoire de Microbiologie, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Paris, France.
Charles SolerService de Biologie Médicale, Hôpital d'Instruction des Armées, Clamart, France.
Jean-Vivien SchaalCentre de Traitement des Brulés, Hôpital d'Instruction des Armées, Clamart, France.
Maurice MimounUniversité Paris Diderot, Sorbonne Paris Cité, Paris, France.
Alexandre MebazaaUMR 942, INSERM, Service d'Anesthésie-Réanimation, Assistance Publique-Hôpitaux de Paris (AP-HP), Groupe Hospitalier Saint-Louis-Lariboisière-Fernand-Widal, Paris, France.
Joseph HeitmanMolecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USA.
Françoise DromerInstitut Pasteur, National Reference Center for Invasive Mycoses and Antifungals (NRCMA), Molecular Mycology Unit, Paris, France.
Sylvain BrisseInstitut Pasteur, Biodiversity and Epidemiology of Bacterial Pathogens, Paris, France.
Stéphane BretagneInstitut Pasteur, National Reference Center for Invasive Mycoses and Antifungals (NRCMA), Molecular Mycology Unit, Paris, France.
Alexandre AlanioInstitut Pasteur, National Reference Center for Invasive Mycoses and Antifungals (NRCMA), Molecular Mycology Unit, Paris, France alexandre.alanio@pasteur.fr.ORCID 0000-0001-9726-3082
Centre National de la Recherche Scientifique · FRAssistance Publique – Hôpitaux de Paris · FRDélégation Paris 7 · FRHôpital d'instruction des Armées Percy · FRInserm · FRDuke Medical Center · USInstitut Pasteur · FRTexas Center for Infectious Disease · US

Funding

Structure, function, and evolution of the Cryptococcus MAT locusR01AI050113 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH · 2002 to 2024
$8.5M
ROLE OF CALCINEURIN IN C. NEOFORMANS MATING AND FRUITINGR01AI039115 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH · 1997 to 2025
$6.7M
Genetics of Cryptococcus sexual reproductionR37AI039115 · NIAID · DUKE UNIVERSITY · PI HEITMAN, JOSEPH · 2011 to 2020
$4.9M
NIAID NIH HHS R01 AI039115NIAID NIH HHS R01 AI050113NIAID NIH HHS R37 AI039115
6 · The paper itself

Abstract

Mucorales are ubiquitous environmental molds responsible for mucormycosis in diabetic, immunocompromised, and severely burned patients. Small outbreaks of invasive wound mucormycosis (IWM) have already been reported in burn units without extensive microbiological investigations. We faced an outbreak of IWM in our center and investigated the clinical isolates with whole-genome sequencing (WGS) analysis. We analyzed

Indexed as

Disease OutbreaksGenetic VariationBurnsBurn UnitsCluster AnalysisCross InfectionFranceGenotypeHumansMolecular EpidemiologyMolecular TypingMucorMucormycosisPhylogenyWhole Genome SequencingWound Infectionburncladegenomegenotypemixed infectionMucoralesMucor circinelloidesmucormycosisoutbreakstrainswhole-genome sequencingwound

Identifiers

PMID29691339
PMCPMC5915733
OpenAlexW2949553117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.