Evidence map›Paper›PMID 29691276›Full record

ArticleGut2018

Asia-Pacific working group consensus on non-variceal upper gastrointestinal bleeding: an update 2018.

Joseph Jy Sung, Philip Wy Chiu, Francis K L Chan, James Yw Lau, Khean-Lee Goh, Lawrence Hy Ho, Hwoon-Young Jung, Jose D Sollano, Takuji Gotoda, Nageshwar Reddy and 8 more

Erratum issued 2 registry-linked trialsAbstract readConsensus Statement
In one paragraph

Article in Gut, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 133 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03814421 naunknown statusnot on this map

Effect of Intermittent Versus Continuous Intravenous Pantoprazole for Prevention of Bleeding After Endoscopic Therapy of Bleeding Peptic Ulcers

TypeinterventionalSponsorSamsung Changwon HospitalRan2016 to 2021Enrolled200ConditionsPeptic Ulcer Hemorrhage, Peptic Ulcer, Acute With Hemorrhage, Peptic Ulcer, Proton Pump Inhibitor OverdoseArmsintermittent (40mg as a bolus injection daily for 72hours)
NCT06659783 completednot on this mapstarted 2024, after this paper: background citation

The First Acute Upper Gastrointestinal Bleeding (AUGIB) Audit in the Greater Bay Area (GBA) of China

Typeobservational_patient_registrySponsorChinese University of Hong KongRan2024 to 2025Enrolled4,534ConditionsAUGIB, Gastrointestinal Bleeding
3 · Its place in the literature

Who cites it

133 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. [Guidelines for Non-variceal Upper Gastrointestinal Bleeding].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2020
    Guideline
  5. Perforated and bleeding peptic ulcer: WSES guidelines.World journal of emergency surgery : WJES · 2020
    Guideline
  6. Guideline
  7. Trial
  8. Time of Resumption of Antiplatelet Drugs After Upper Gastrointestinal Hemorrhage.Medical science monitor : international medical journal of experimental and clinical research · 2022
    Trial
  9. Trial
  10. Randomized Controlled Trial of Over-the-Scope Clip as Initial Treatment of Severe Nonvariceal Upper Gastrointestinal Bleeding.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2021
    Trial
  11. Trial
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Pharmacological Management of Peptic Ulcer Bleeding.The Korean journal of helicobacter and upper gastrointestinal research · 2026
    Review
  19. Article
  20. Management of Non-Variceal Upper Gastrointestinal Bleeding.The Korean journal of helicobacter and upper gastrointestinal research · 2026
    Review

73 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Joseph Jy SungInstitute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong.
Philip Wy ChiuInstitute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong.
Francis K L ChanInstitute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong.ORCID 0000-0001-7388-2436
James Yw LauInstitute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong.
Khean-Lee GohDepartment of Gastroenterology and Hepatology, University of Malaya, Kuala Lumpur, Malaysia.
Lawrence Hy HoYong Loo Lin School of Medicine, National University of Singapore, Singapore.
Hwoon-Young JungUniversity of Ulsan College of Medicine, Ulsan, South Korea.
Jose D SollanoUST Hospital, University of Santo Tomas, Manila, Philippines.
Takuji GotodaDivision of Gastroenterology and Hepatology, Nihon University School of Medicine, Tokyo, Japan.
Nageshwar ReddyAsian Institute of Gastroenterology, Asian Healthcare Foundation, Hyderabad, India.
Rajvinder SinghDepartment of Medicine, Lyell McEwin Hospital, University of Adelaide, Adelaide, South Australia, Australia.
Kentaro SuganoDepartment of Medicine, Jichi Medical School, Shimotsuke, Japan.
Kai-Chun WuState Key Laboratory of Cancer Biology, Xijing Hospital of Digestive Diseases, Xi'an, China.
Chun-Yin WuChina Medical University, Taichung, Taiwan.
David J BjorkmanUniversity of Utah College of Health, Salt Lake City, Utah, USA.
Dennis M JensenUniversity of California, Los Angeles, California, USA.
Ernst J KuipersDepartment of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Angel LanasDepartment of Gastroenterology, University Hospital, Zaragoza, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-variceal upper gastrointestinal bleeding remains an important emergency condition, leading to significant morbidity and mortality. As endoscopic therapy is the 'gold standard' of management, treatment of these patients can be considered in three stages: pre-endoscopic treatment, endoscopic haemostasis and post-endoscopic management. Since publication of the Asia-Pacific consensus on non-variceal upper gastrointestinal bleeding (NVUGIB) 7 years ago, there have been significant advancements in the clinical management of patients in all three stages. These include pre-endoscopy risk stratification scores, blood and platelet transfusion, use of proton pump inhibitors; during endoscopy new haemostasis techniques (haemostatic powder spray and over-the-scope clips); and post-endoscopy management by second-look endoscopy and medication strategies. Emerging techniques, including capsule endoscopy and Doppler endoscopic probe in assessing adequacy of endoscopic therapy, and the pre-emptive use of angiographic embolisation, are attracting new attention. An emerging problem is the increasing use of dual antiplatelet agents and direct oral anticoagulants in patients with cardiac and cerebrovascular diseases. Guidelines on the discontinuation and then resumption of these agents in patients presenting with NVUGIB are very much needed. The Asia-Pacific Working Group examined recent evidence and recommends practical management guidelines in this updated consensus statement.

Indexed as

Gastrointestinal HemorrhagePeptic Ulcer HemorrhagePractice Guidelines as TopicConsensusEmbolization, TherapeuticEndoscopy, GastrointestinalHumansPatient SelectionPlatelet Aggregation InhibitorsProton Pump InhibitorsRecurrenceReoperationRisk AssessmentPlatelet Aggregation InhibitorsProton Pump Inhibitorsendoscopygastrointestinal bleeding

Identifiers

PMID29691276
PMCPMC6145289

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.