Evidence map›Paper›PMID 29691225›Full record

ArticleDevelopment (Cambridge, England)2018

Suppression of epithelial folding at actomyosin-enriched compartment boundaries downstream of Wingless signalling in

Jose M Urbano, Huw W Naylor, Elena Scarpa, Leila Muresan, Bénédicte Sanson

Abstract read
In one paragraph

Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jose M UrbanoDepartment of Physiology, Development and Neuroscience, University of Cambridge, Anatomy Building, Downing Street, Cambridge, CB2 3DY, UK.ORCID 0000-0002-6644-8129
Huw W NaylorDepartment of Physiology, Development and Neuroscience, University of Cambridge, Anatomy Building, Downing Street, Cambridge, CB2 3DY, UK.ORCID 0000-0001-8264-8596
Elena ScarpaDepartment of Physiology, Development and Neuroscience, University of Cambridge, Anatomy Building, Downing Street, Cambridge, CB2 3DY, UK.ORCID 0000-0002-0849-1276
Leila MuresanDepartment of Physiology, Development and Neuroscience, University of Cambridge, Anatomy Building, Downing Street, Cambridge, CB2 3DY, UK.ORCID 0000-0002-7602-0249
Bénédicte SansonDepartment of Physiology, Development and Neuroscience, University of Cambridge, Anatomy Building, Downing Street, Cambridge, CB2 3DY, UK bs251@cam.ac.uk.ORCID 0000-0002-2782-4195

Funding

Biotechnology and Biological Sciences Research Council BB/J010278/1Wellcome Trust 099130/Z/12/ZWellcome Trust 099234/Z/12/ZWellcome Trust 207553/Z/17/Z
6 · The paper itself

Abstract

Epithelial folding shapes embryos and tissues during development. Here, we investigate the coupling between epithelial folding and actomyosin-enriched compartmental boundaries. The mechanistic relationship between the two is unclear, because actomyosin-enriched boundaries are not necessarily associated with folds. Also, some cases of epithelial folding occur independently of actomyosin contractility. We investigated the shallow folds called parasegment grooves that form at boundaries between anterior and posterior compartments in the early

Indexed as

ActomyosinAdherens JunctionsAnimalsAnimals, Genetically ModifiedBacterial ProteinsBody PatterningDrosophila melanogasterDrosophila ProteinsEpitheliumGene Knockdown TechniquesGenes, InsectGreen Fluorescent ProteinsHedgehog ProteinsIntracellular Signaling Peptides and ProteinsLuminescent ProteinsMutationActomyosinBacterial Proteinsbaz protein, DrosophilaDrosophila ProteinsGreen Fluorescent ProteinsHedgehog Proteinshh protein, DrosophilaIntracellular Signaling Peptides and ProteinsLuminescent ProteinsMyosin-Light-Chain PhosphataseMyosin Type IIwg protein, DrosophilaWnt1 Proteinyellow fluorescent protein, BacteriaApico-basal polarityContractilityEmbryoEpitheliumMorphogenesisPlanar polarity

Identifiers

PMID29691225
PMCPMC5964650

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.