Evidence map›Paper›PMID 29691222›Full record

ArticleClinical chemistry2018

Checkpoint Checkmate: Microbiota Modulation of Cancer Immunotherapy.

Eric C Keen, Terence S Crofts, Gautam Dantas

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Modeling the Th17 and Tregs Paradigm: Implications for Cancer Immunotherapy.Frontiers in cell and developmental biology · 2021
    Review
  6. Complex interactions between the microbiome and cancer immune therapy.Critical reviews in clinical laboratory sciences · 2019
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Eric C KeenThe Edison Family Center for Genome Sciences and Systems Biology, Washington University in St. Louis School of Medicine, Saint Louis, MO.
Terence S CroftsThe Edison Family Center for Genome Sciences and Systems Biology, Washington University in St. Louis School of Medicine, Saint Louis, MO.
Gautam DantasThe Edison Family Center for Genome Sciences and Systems Biology, Washington University in St. Louis School of Medicine, Saint Louis, MO; dantas@wustl.edu.

Funding

Pediatric Gastroenterology Research Training ProgramT32DK077653 · NIDDK · WASHINGTON UNIVERSITY · PI PHILLIP I TARR · 2007 to 2026
$5.8M
STRUCTURAL, MECHANISTIC, & EVOLUTIONARY CHARACTERIZATION OF TETRACYCLINE DESTRUCTASESU01AI123394 · NIAID · WASHINGTON UNIVERSITY · PI DANTAS, GAUTAM, WENCEWICZ, TIMOTHY ADAM · 2020 to 2025
$4.1M
PHYLOGENOMIC, TRANSCRIPTOMIC, VIROMIC, AND IMMUNOPROTEOMIC DETERMINANTS OF NECROTIZING ENTEROCOLITISR01HD092414 · NICHD · WASHINGTON UNIVERSITY · PI DANTAS, GAUTAM, TARR, PHILLIP I · 2017 to 2021
$3.0M
STRUCTURAL, MECHANISTIC, & EVOLUTIONARY CHARACTERIZATION OF TETRACYCLINE DESTRUCTASESR01AI123394 · NIAID · WASHINGTON UNIVERSITY · PI DANTAS, GAUTAM, WENCEWICZ, TIMOTHY ADAM · 2016 to 2019
$2.7M
Training in Reproductive SciencesT32HD049305 · NICHD · WASHINGTON UNIVERSITY · PI MOLEY, KELLE H · 2005 to 2015
$1.9M
NIAID NIH HHS R01 AI123394NIAID NIH HHS U01 AI123394NICHD NIH HHS R01 HD092414NICHD NIH HHS T32 HD049305NIDDK NIH HHS T32 DK077653
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gastrointestinal MicrobiomeMelanomaMicrobiotaHumansImmunotherapyProgrammed Cell Death 1 ReceptorProgrammed Cell Death 1 Receptor

Identifiers

PMID29691222
PMCPMC6436377

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.