ArticleJournal of neurotrauma2018
A Comparison of Oxidative Lactate Metabolism in Traumatically Injured Brain and Control Brain.
Article in Journal of neurotrauma, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Effects of lactate-based therapies on intracranial pressure and brain metabolism of patients with acute brain injury: a systematic review.Critical care (London, England) · 2026Pooled it
- Unlocking the metabolic and anti-inflammatory therapeutic potential of lactate in critically ill patients.Critical care (London, England) · 2025Review
- Longitudinal Brain Structural, Neurochemical, and Behavioral Changes Following Traumatic Brain Injury in Immature Rat Brain with ALCAR Treatment.Neurochemical research · 2025Article
- Association Between the Highest Lactate Level on the First Postoperative Day and Postoperative Delirium in Cardiac Surgery Patients.CNS neuroscience & therapeutics · 2025Article
- Defining metabolic abnormalities in acute human traumatic brain injury with cerebral microdialysis and multimodality monitoring.PloS one · 2025Article
- Tracing the path of disruption:CNS neuroscience & therapeutics · 2024Review
- Integrated Transcriptomics and Metabolomics Reveal Changes in Cell Homeostasis and Energy Metabolism inInternational journal of molecular sciences · 2024Article
- Associations of serum lactate and lactate clearance with delirium in the early stage of ICU: a retrospective cohort study of the MIMIC-IV database.Frontiers in neurology · 2024Article
- High-physiological and supra-physiological 1,2-Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- Repeated Low-Level Blast Exposure Alters Urinary and Serum Metabolites.Metabolites · 2023Article
- Serum lactate monitoring may help to predict neurological function impairment caused by acute metabolism crisis.Scientific reports · 2023Article
- An overview of clinical cerebral microdialysis in acute brain injury.Frontiers in neurology · 2023Review
- Lactate infusion as therapeutical intervention: a scoping review.European journal of pediatrics · 2022Article
- Monitoring Neurochemistry in Traumatic Brain Injury Patients Using Microdialysis Integrated with Biosensors: A Review.Metabolites · 2022Review
- Metabolic derangements are associated with impaired glucose delivery following traumatic brain injury.Brain : a journal of neurology · 2021Observational
- Tumor metabolism and neurocognition in CNS lymphoma.Neuro-oncology · 2021Article
- Characterising the dynamics of cerebral metabolic dysfunction following traumatic brain injury: A microdialysis study in 619 patients.PloS one · 2021Article
- A Prospective Observational Feasibility Study of Jugular Bulb Microdialysis in Subarachnoid Hemorrhage.Neurocritical care · 2020Observational
- Nutrition Therapy, Glucose Control, and Brain Metabolism in Traumatic Brain Injury: A Multimodal Monitoring Approach.Frontiers in neuroscience · 2020Review
- A Novel, Multi-Faceted Perception of Lactate in Neurology.Frontiers in neuroscience · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 1 institution in 1 country.
Funding
Abstract
Metabolic abnormalities occur after traumatic brain injury (TBI). Glucose is conventionally regarded as the major energy substrate, although lactate can also be an energy source. We compared 3-
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.