Evidence map›Paper›PMID 29690798›Full record

ArticleThe Journal of international medical research2018

Acute chemotherapy-induced nausea and vomiting in children with cancer: Still waiting for a common consensus on treatment.

Antonio Ruggiero, Daniela Rizzo, Martina Catalano, Paola Coccia, Silvia Triarico, Giorgio Attiná

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. An insight into real-world practice: What information sources inform the prescribing for children with cancer in Scotland? A focus on emesis, tumour lysis syndrome (TLS), andJournal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Evaluation of Olanzapine for the Prevention of Refractory Chemotherapy-Induced Vomiting in Pediatric Oncology Patients.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025
    Article
  7. Observational
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Guideline concordant care for prevention of acute chemotherapy-induced nausea and vomiting in children, adolescents, and young adults.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Antonio Ruggiero1 Pediatric Oncology Unit, A. Gemelli Hospital, Catholic University of Rome, Rome, Italy.ORCID http://orcid.org/0000-0002-6052-3511
Daniela Rizzo1 Pediatric Oncology Unit, A. Gemelli Hospital, Catholic University of Rome, Rome, Italy.
Martina Catalano1 Pediatric Oncology Unit, A. Gemelli Hospital, Catholic University of Rome, Rome, Italy.
Paola Coccia2 Department of Paediatric Haemato-Oncology, Ospedale G. Salesi, Ancona, Italy.
Silvia Triarico1 Pediatric Oncology Unit, A. Gemelli Hospital, Catholic University of Rome, Rome, Italy.
Giorgio Attiná1 Pediatric Oncology Unit, A. Gemelli Hospital, Catholic University of Rome, Rome, Italy.
Agostino Gemelli University Polyclinic · ITFondazione Ospedale Salesi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemotherapy-induced nausea and vomiting (CINV) is one of the most common treatment side-effects, and remains a significant concern, in children undergoing chemotherapy. Although adult patients receive chemotherapy regimens combined with appropriate standardized antiemetic treatment, children can receive markedly varying antiemetic treatments. A narrative review of CINV was performed regarding CINV definition, scoring system, prevention and treatment, specifically focussing on studies conducted with paediatric oncology patients. The review highlighted a lack of rigorously developed CINV scoring systems and standardized CINV pharmacological treatment for paediatric oncology patients. Different scoring systems were found to identify potential risk factors for CINV associated with the use of several different antiemetic drugs, however, few studies have been performed in children undergoing chemotherapy. Thus, CINV remains a distressing and partially controlled side-effect in the paediatric patient population. To reduce emesis and improve quality of life in paediatric oncology patients, standardized antiemetic treatment may be preferred, using a unique CINV scoring system that accounts for the emetogenic level of the chemotherapy regimen adopted and the children's clinical characteristics.

Indexed as

Severity of Illness IndexAdultAntiemeticsAntineoplastic AgentsChildConsensusHumansNauseaNeoplasmsQuality of LifeVomitingAntiemeticsAntineoplastic AgentscancerchemotherapychildrenCINVpaediatric

Identifiers

PMID29690798
PMCPMC6023075
OpenAlexW2801320241

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.