Evidence map›Paper›PMID 29689191›Full record

ArticleDevelopmental cell2018

Myonuclear Positioning and Aneurysms Are LINC'd by Ariande.

Mridula Balakrishnan, Mary K Baylies

Erratum issuedAbstract readComment
In one paragraph

Article in Developmental cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Mridula BalakrishnanProgram in Biochemistry, Cell and Molecular Biology, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA; Program in Developmental Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Mary K BayliesProgram in Biochemistry, Cell and Molecular Biology, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA; Program in Developmental Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: m-baylies@ski.mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Mechanisms and Function of Myonuclear PositioningR01AR068128 · NIAMS · SLOAN-KETTERING INST CAN RESEARCH · PI BAYLIES, MARY K · 2014 to 2025
$5.1M
Sizing and Scaling in Functional Muscle CellsR01GM121971 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI BAYLIES, MARY K · 2017 to 2020
$1.8M
Therapeutic target discovery in Drosophila models of Nemaline MyopathyR21AR067361 · NIAMS · SLOAN-KETTERING INST CAN RESEARCH · PI BAYLIES, MARY K · 2015 to 2016
$426k
NCI NIH HHS P30 CA008748NIAMS NIH HHS R01 AR068128NIAMS NIH HHS R21 AR067361NIGMS NIH HHS R01 GM121971
6 · The paper itself

Abstract

In this issue of Developmental Cell, Tan et al. (2018) show how a novel player in myonuclear positioning, the ubiquitin ligase Ari-1, regulates levels of Koi, a member of the LINC mechanosensing complex, and affects nuclear morphology and positioning in both Drosophila muscles and human vascular smooth muscle cells.

Indexed as

Cell NucleusNuclear EnvelopeAneurysmAnimalsDrosophilaHumansMuscles

Identifiers

PMID29689191
PMCPMC5937272

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.