Evidence map›Paper›PMID 29688939›Full record

ReviewCurrent opinion in critical care2018

In-hospital cardiac arrest: are we overlooking a key distinction?

Ari Moskowitz, Mathias J Holmberg, Michael W Donnino, Katherine M Berg

Registry-linked trialAbstract readComparative StudyReview
In one paragraph

Review in Current opinion in critical care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05520762 (Hospital Airway Resuscitation Trial), which is not on this map. Cited by 23 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05520762 narecruitingnot on this mapstarted 2023, after this paper: background citation

Hospital Airway Resuscitation Trial: A Cluster-Randomized, Pragmatic Trial

TypeinterventionalSponsorMontefiore Medical CenterRan2023 to 2027Enrolled1,060ConditionsCardiac Arrest, Respiratory FailureArmsA strategy of first choice supraglottic airway, A strategy of first choice endotracheal intubation
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. The use and impact of prehospital blood lactate measurements in acute non-traumatic patients: a systematic review.Scandinavian journal of trauma, resuscitation and emergency medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ari MoskowitzDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.
Mathias J HolmbergDepartment of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Michael W DonninoDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.
Katherine M BergDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine.

Funding

Training Program in Cardiovascular ResearchT32HL007374 · NHLBI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI MITTLEMAN, MURRAY A · 1985 to 2019
$7.9M
Thaimine as an adjunct metabolic resuscitator in cardiac arrestK24HL127101 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI DONNINO, MICHAEL WILLIAM · 2015 to 2024
$1.2M
Thiamine v placebo to improve oxygen consumption after in-hospital cardiac arrestK23HL128814 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BERG, KATHERINE M · 2016 to 2021
$1.0M
Thiamine as a Renal Protective Agent in Septic ShockK23GM128005 · NIGMS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI MOSKOWITZ, ARI · 2018 to 2021
$761k
NHLBI NIH HHS K23 HL128814NHLBI NIH HHS K24 HL127101NHLBI NIH HHS T32 HL007374NIGMS NIH HHS K23 GM128005
6 · The paper itself

Abstract

purpose of reviewTo review the epidemiology, peri-arrest management, and research priorities related to in-hospital cardiac arrest (IHCA) and explore key distinctions between IHCA and out-of-hospital cardiac arrest (OHCA) as they pertain to the clinician and resuscitation scientist. RECENT

findingsIHCA is a common and highly morbid event amongst hospitalized patients in the United States. As compared with patients who experience an OHCA, patients who experience an IHCA tend to have more medical comorbidities, have a witnessed arrest, and be attended to by professional first responders. Further, providers resuscitating patients from IHCA commonly have access to tools and information not readily available to the OHCA responders. Despite these differences, society guidelines for the peri-arrest management of patients with IHCA are often based on data extrapolated from the OHCA population. To advance the care of patients with IHCA, clinicians and investigators should recognize the many important distinctions between OHCA and IHCA. SUMMARY: IHCA is a unique disease entity with an epidemiology and natural history that are distinct from OHCA. In both research and clinical practice, physicians should recognize these distinctions so as to advance the care of IHCA victims.

Indexed as

Practice Guidelines as TopicAdultAgedAged, 80 and overCardiopulmonary ResuscitationEmergency Medical ServicesFemaleHeart ArrestHumansMaleMiddle AgedOut-of-Hospital Cardiac ArrestSurvival RateTreatment OutcomeUnited States

Identifiers

PMID29688939
PMCPMC6007985

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.