ArticleMicrobial drug resistance (Larchmont, N.Y.)2018
Genomic Characterization of Nonclonal mcr-1-Positive Multidrug-Resistant Klebsiella pneumoniae from Clinical Samples in Thailand.
Article in Microbial drug resistance (Larchmont, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 37 citations in OpenAlex.
- The Co-Existence ofAntibiotics (Basel, Switzerland) · 2025Article
- Genomic analysis of carbapenem- and colistin-resistant Klebsiella pneumoniae complex harbouring mcr-8 and mcr-9 from individuals in Thailand.Scientific reports · 2024Article
- Exploring the epidemiology of mcr genes, genetic context and plasmids in Enterobacteriaceae originating from pigs and humans on farms in Thailand.The Journal of antimicrobial chemotherapy · 2023Article
- Evidence of international transmission of mobile colistin resistant monophasic Salmonella Typhimurium ST34.Scientific reports · 2023Article
- Identification and characterization of plasmids carrying the mobile colistin resistance geneJAC-antimicrobial resistance · 2023Article
- Plasmidome in mcr-1 harboring carbapenem-resistant enterobacterales isolates from human in Thailand.Scientific reports · 2022Article
- Molecular characterization of multidrug-resistant ESKAPEE pathogens from clinical samples in Chonburi, Thailand (2017-2018).BMC infectious diseases · 2022Article
- Nationwide surveillance in Thailand revealed genotype-dependent dissemination of carbapenem-resistantMicrobial genomics · 2022Article
- Occurrence of mcr-mediated colistin resistance in Salmonella clinical isolates in Thailand.Scientific reports · 2021Article
- Genomic and clinical characterisation of multidrug-resistant carbapenemase-producing ST231 and ST16 Klebsiella pneumoniae isolates colonising patients at Siriraj hospital, Bangkok, Thailand from 2015 to 2017.BMC infectious diseases · 2021Article
- Characterization of aFrontiers in microbiology · 2021Article
- Reducing the Risk of Transmission of Critical Antimicrobial Resistance Determinants From Contaminated Pork Products to Humans in South-East Asia.Frontiers in microbiology · 2021Review
- Plasmid MediatedFrontiers in microbiology · 2021Article
- Novel IncR/IncP6 Hybrid Plasmid pCRE3-KPC Recovered from a Clinical KPC-2-Producing Citrobacter braakii Isolate.mSphere · 2020Article
- In vitro activity of ceftazidime/avibactam against isolates of carbapenem-non-susceptible Enterobacteriaceae collected during the INFORM global surveillance programme (2015-17).The Journal of antimicrobial chemotherapy · 2020Article
- A Department of Defense Laboratory Consortium Approach to Next Generation Sequencing and Bioinformatics Training for Infectious Disease Surveillance in Kenya.Frontiers in genetics · 2020Article
- Whole-Genome Sequencing of Clinically Isolated Carbapenem-Resistant Enterobacterales HarboringFrontiers in microbiology · 2020Article
- Characterization of a NDM-1- Encoding Plasmid pHFK418-NDM From a ClinicalFrontiers in microbiology · 2019Article
- Non-clonal occurrence of pmrB mutations associated with polymyxin resistance in carbapenem-resistant Klebsiella pneumoniae in Brazil.Memorias do Instituto Oswaldo Cruz · 2019Article
- PCR-Dipstick-Oriented Surveillance and Characterization ofFrontiers in microbiology · 2019Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multidrug-resistant Klebsiella pneumoniae strains are one of the most prevalent causes of nosocomial infections and pose an increasingly dangerous public health threat. The lack of remaining treatment options has resulted in the utilization of older drug classes, including colistin. As a drug of last resort, the discovery of plasmid-mediated colistin resistance by mcr-1 denotes the potential development of pandrug-resistant bacterial pathogens. To address the emergence of the mcr-1 gene, 118 gram-negative Enterobacteriaceae isolated from clinical samples collected at Queen Sirikit Naval Hospital in Chonburi, Thailand were screened for colistin resistance using automated antimicrobial susceptibility testing and conventional PCR screening. Two K. pneumoniae strains, QS17-0029 and QS17-0161, were positive for mcr-1, and both isolates were sequenced to closure using short- and long-read whole-genome sequencing. QS17-0029 carried 16 antibiotic resistance genes in addition to mcr-1, including 2 carbapenemases, bla
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