ArticleMolecular biology and evolution2018
Insights into Platypus Population Structure and History from Whole-Genome Sequencing.
Article in Molecular biology and evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- A macrogenetic analysis of isolation mechanisms shaping genetic divergence in mammals.The Journal of heredity · 2026Pooled it
- Genotyping-by-sequencing of Illicium difengpi highlights its potential genetic diversity and conservation status.Scientific reports · 2025Article
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- Chromosome-level echidna genome illuminates evolution of multiple sex chromosome system in monotremes.GigaScience · 2025Article
- Applying a modified streamlined disease risk analysis framework to a platypus conservation translocation, with special consideration for the conservation of ecto- and endoparasites.International journal for parasitology. Parasites and wildlife · 2024Article
- Demographic history and genomic signatures of selection in a widespread vertebrate ectotherm.Molecular ecology · 2024Article
- De Novo Mutation Rates in Sticklebacks.Molecular biology and evolution · 2023Article
- Article
- Fragmentation by major dams and implications for the future viability of platypus populations.Communications biology · 2022Article
- Article
- Pedigree-based and phylogenetic methods support surprising patterns of mutation rate and spectrum in the gray mouse lemur.Heredity · 2021Article
- Article
- Population analysis of the Korean native duck using whole-genome sequencing data.BMC genomics · 2020Article
- A practical introduction to sequentially Markovian coalescent methods for estimating demographic history from genomic data.Ecology and evolution · 2020Review
- Network-based hierarchical population structure analysis for large genomic data sets.Genome research · 2019Article
- Evidence that DNA repair genes, a family of tumor suppressor genes, are associated with evolution rate and size of genomes.Human genomics · 2019Article
- The platypus: evolutionary history, biology, and an uncertain future.Journal of mammalogy · 2019Article
Corrections and comments
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Authors and funding
14 authors at 7 institutions in 3 countries.
Funding
Abstract
The platypus is an egg-laying mammal which, alongside the echidna, occupies a unique place in the mammalian phylogenetic tree. Despite widespread interest in its unusual biology, little is known about its population structure or recent evolutionary history. To provide new insights into the dispersal and demographic history of this iconic species, we sequenced the genomes of 57 platypuses from across the whole species range in eastern mainland Australia and Tasmania. Using a highly improved reference genome, we called over 6.7 M SNPs, providing an informative genetic data set for population analyses. Our results show very strong population structure in the platypus, with our sampling locations corresponding to discrete groupings between which there is no evidence for recent gene flow. Genome-wide data allowed us to establish that 28 of the 57 sampled individuals had at least a third-degree relative among other samples from the same river, often taken at different times. Taking advantage of a sampled family quartet, we estimated the de novo mutation rate in the platypus at 7.0 × 10-9/bp/generation (95% CI 4.1 × 10-9-1.2 × 10-8/bp/generation). We estimated effective population sizes of ancestral populations and haplotype sharing between current groupings, and found evidence for bottlenecks and long-term population decline in multiple regions, and early divergence between populations in different regions. This study demonstrates the power of whole-genome sequencing for studying natural populations of an evolutionarily important species.
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