Evidence map›Paper›PMID 29687949›Full record

ArticleCell proliferation2018

1,25(OH)

Dong Sun, Fei Luo, Jun-Chao Xing, Fei Zhang, Jian-Zhong Xu, Ze-Hua Zhang

Open access · bronzeAbstract read
In one paragraph

Article in Cell proliferation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Vitamin D and Brain Health.Advances in experimental medicine and biology · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Maternal vitamin D supplementation inhibits bisphenol A-induced proliferation of Th17 cells in adult offspring.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2020
    Article
  18. CYP11A1-derived vitamin DFree radical biology & medicine · 2020
    Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dong SunDepartment of Orthopaedics, Southwest Hospital, Third Military Medical University, Chongqing, China.
Fei LuoDepartment of Orthopaedics, Southwest Hospital, Third Military Medical University, Chongqing, China.
Jun-Chao XingDepartment of Orthopaedics, Southwest Hospital, Third Military Medical University, Chongqing, China.
Fei ZhangDepartment of Orthopaedics, Southwest Hospital, Third Military Medical University, Chongqing, China.
Jian-Zhong XuDepartment of Orthopaedics, Southwest Hospital, Third Military Medical University, Chongqing, China.
Ze-Hua ZhangDepartment of Orthopaedics, Southwest Hospital, Third Military Medical University, Chongqing, China.ORCID http://orcid.org/0000-0002-1944-6438
Army Medical University · CN

Funding

National Science Foundation of China 81371980National Science Foundation of China 81401816
6 · The paper itself

Abstract

objectivesThe role of vitamin D (VD) in innate and adaptive immune responses to tuberculosis is still unclear. Our research was aimed to uncover the effect of VD on Th17 cells and elucidate potential molecular mechanism. MATERIALS AND

methodsVDR-deficient and wild-type mice were used to obtain CD4 T cells. Th17 cells were induced and activated by Bacillus Calmette Guerin. Flow cytometry was used to analyse the apoptosis rate and degree of differentiation of Th17 cells in the treatment of 1,25(OH)

resultsThe Th17 cells differentiation was suppressed by 1,25(OH)

conclusionsTogether, 1,25(OH)

Indexed as

AnimalsApoptosisCalcitriolCD4-Positive T-LymphocytesCell DifferentiationGene Expression RegulationInterleukin-17MiceMice, Inbred C57BLNF-kappa BNuclear Receptor Subfamily 1, Group F, Member 3Receptors, CalcitriolSignal TransductionTh17 CellsTranscription Factor RelACalcitriolInterleukin-17NF-kappa BNuclear Receptor Subfamily 1, Group F, Member 3Receptors, CalcitriolTranscription Factor RelA1,25(OH)2D3IL-17NF-κBTh17 cells differentiationVDR

Identifiers

PMID29687949
PMCPMC6528876
OpenAlexW2800118051

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.