ReviewCNS neuroscience & therapeutics2018
Understanding jugular venous outflow disturbance.
Review in CNS neuroscience & therapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 71 citations in OpenAlex.
- Multi-position head-and-neck rotational CT venography evaluation of dynamic changes in internal jugular vein compression in patients with an elongated styloid process.Quantitative imaging in medicine and surgery · 2026Article
- Cerebral blood flow alterations in non-auditory tinnitus: implications for cerebral venous congestion pathophysiology.Brain imaging and behavior · 2026Article
- Characterizing Initial Cervical Spine and Neurovascular Findings in 84 Consecutive Patients with Hypermobile Ehlers-Danlos Syndrome: A Retrospective Study.Journal of clinical medicine · 2026Article
- Narrower jugular bulbs and their tributaries are associated with skull base venous hyperintensity on arterial spin-labeling MRI.Scientific reports · 2026Article
- Cerebral Venous Outflow Insufficiency: A Study on Symptoms and Venous Stenosis Classification.MedComm · 2026Article
- Complication of stent displacement from the internal jugular vein to the pulmonary artery after jugular vein stenting in the treatment of intracranial hypertension: a case report.BMC neurology · 2025Article
- Cervical Oculopathy: The Cervical Spine Etiology of Visual Symptoms and Eye Diseases-A Hypothesis Exploring Mechanisms Linking the Neck and the Eye.Diagnostics (Basel, Switzerland) · 2025Article
- Headache in Patients With Non-Thrombotic Internal Jugular Vein Stenosis: Clinical Characteristics and Associated Risk Factors in a Retrospective Study of 283 Cases.CNS neuroscience & therapeutics · 2025Article
- Ultrasound Evaluation of Internal Jugular Venous Insufficiency and Its Association with Cognitive Decline.Diagnostics (Basel, Switzerland) · 2025Article
- Treatment of thoracic outlet syndrome to relieve chronic migraine.Clinical anatomy (New York, N.Y.) · 2025Observational
- Case Report: Unveiling segmental hemodynamic heterogeneity in internal jugular vein stenosis: a patient-specific CFD analysis.Frontiers in cardiovascular medicine · 2025Article
- Objective test findings in patients with chronic eye symptoms seeking care at an outpatient neck center: ligamentous cervical instability etiology?Frontiers in neurology · 2025Article
- Chemical Denervation to Relieve Symptoms in Jugular Venous Compression Syndrome: A Case Report.Case reports in vascular medicine · 2025Article
- Self-Induced Stretch Syncope: An Unusual Non-Epileptic Paroxysmal Event. A Case Report and Literature Mini-Review.Clinical medicine insights. Pediatrics · 2024Article
- Extreme lateral infracondylar approach for internal jugular vein compression syndrome: A case series with preliminary clinical outcomes.Acta neurochirurgica · 2023Article
- Long-term safety and efficacy of stenting on correcting internal jugular vein and cerebral venous sinus stenosis.Annals of clinical and translational neurology · 2023Article
- Results of Numerical Modeling of Blood Flow in the Internal Jugular Vein Exhibiting Different Types of Strictures.Diagnostics (Basel, Switzerland) · 2022Article
- Differentiation between anatomical slenderness and acquired stenosis of the internal jugular veins.CNS neuroscience & therapeutics · 2022Article
- The BE COOL Treatments (Batroxobin, oxygEn, Conditioning, and cOOLing): Emerging Adjunct Therapies for Ischemic Cerebrovascular Disease.Journal of clinical medicine · 2022Review
- Persistent headaches sometimes concern incidental findings: A rare case of internal jugular vein agenesis in a 32-year-old man.Clinical case reports · 2022Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extracranial venous abnormalities, especially jugular venous outflow disturbance, were originally viewed as nonpathological phenomena due to a lack of realization and exploration of their feature and clinical significance. The etiology and pathogenesis are still unclear, whereas a couple of causal factors have been conjectured. The clinical presentation of this condition is highly variable, ranging from insidious to symptomatic, such as headaches, dizziness, pulsatile tinnitus, visual impairment, sleep disturbance, and neck discomfort or pain. Standard diagnostic criteria are not available, and current diagnosis largely depends on a combinatory use of imaging modalities. Although few researches have been conducted to gain evidence-based therapeutic approach, several recent advances indicate that intravenous angioplasty in combination with stenting implantation may be a safe and efficient way to restore normal blood circulation, alleviate the discomfort symptoms, and enhance patients' quality of life. In addition, surgical removal of structures that constrain the internal jugular vein may serve as an alternative or adjunctive management when endovascular intervention is not feasible. Notably, discussion on every aspect of this newly recognized disease entity is in the infant stage and efforts with more rigorous designed, randomized controlled studies in attempt to identify the pathophysiology, diagnostic criteria, and effective approaches to its treatment will provide a profound insight into this issue.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.