ArticleHLA2018
The major histocompatibility complex homozygous inbred Babraham pig as a resource for veterinary and translational medicine.
Article in HLA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Duration of immunity following infection with moderately virulent ASFV.PLoS pathogens · 2026Article
- Voluntary Additional Welfare Monitoring of Farm Animals Used in Research: Maximising Benefits Requires Sustained Support.Animals : an open access journal from MDPI · 2025Article
- A genome assembly and transcriptome atlas of the inbred Babraham pig to illuminate porcine immunogenetic variation.Immunogenetics · 2024Article
- Single-cell analysis reveals lasting immunological consequences of influenza infection and respiratory immunization in the pig lung.PLoS pathogens · 2024Article
- The transcriptomic insight into the differential susceptibility of African Swine Fever in inbred pigs.Scientific reports · 2024Article
- Comparative analysis of swine leukocyte antigen gene diversity in Göttingen Minipigs.Frontiers in immunology · 2024Article
- Capsid-Specific Antibody Responses of Domestic Pigs Immunized with Low-Virulent African Swine Fever Virus.Vaccines · 2023Article
- Effect of mucosal adjuvant IL-1β on heterotypic immunity in a pig influenza model.Frontiers in immunology · 2023Article
- Article
- Genomic consequences of a century of inbreeding and isolation in the Danish wild boar population.Evolutionary applications · 2022Article
- Spatial, temporal and molecular dynamics of swine influenza virus-specific CD8 tissue resident memory T cells.Mucosal immunology · 2022Article
- Comparative analysis of swine leukocyte antigen gene diversity in European farmed pigs.Animal genetics · 2021Article
- A comparative analysis of SLA-DRB1 genetic diversity in Colombian (creoles and commercial line) and worldwide swine populations.Scientific reports · 2021Article
- Diversity of the Swine Leukocyte Antigen Class I and II in Commercial Pig Populations.Frontiers in veterinary science · 2021Article
- A Pool of Eight Virally Vectored African Swine Fever Antigens Protect Pigs Against Fatal Disease.Vaccines · 2020Article
- Magnitude and Kinetics of T Cell and Antibody Responses During H1N1pdm09 Infection in Inbred Babraham Pigs and Outbred Pigs.Frontiers in immunology · 2020Article
- Identification of a Newly Conserved SLA-II Epitope in a Structural Protein of Swine Influenza Virus.Frontiers in immunology · 2020Article
- The Veterinary Immunological Toolbox: Past, Present, and Future.Frontiers in immunology · 2020Review
- Identification and Immunogenicity of African Swine Fever Virus Antigens.Frontiers in immunology · 2019Article
- T and B Cell Immune Responses to Influenza Viruses in Pigs.Frontiers in immunology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
The Babraham pig is a highly inbred breed first developed in the United Kingdom approximately 50 years ago. Previous reports indicate a very high degree of homozygosity across the genome, including the major histocompatibility complex (MHC) region, but confirmation of homozygosity at the specific MHC loci was lacking. Using both direct sequencing and PCR-based sequence-specific typing, we confirm that Babraham pigs are essentially homozygous at their MHC loci and formalise their MHC haplotype as Hp-55.6. This enhances the utility of the Babraham pig as a useful biomedical model for studies in which controlling for genetic variation is important.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.