Evidence map›Paper›PMID 29687403›Full record

ArticleJournal of neurovirology2018

Progressive multifocal leukoencephalopathy in idiopathic CD4+ lymphocytopenia.

Rajeswari Aghoram, Sunil K Narayan

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Journal of neurovirology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Progressive multifocal leukoencephalopathy in patients with chronic kidney disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Article
  2. Idiopathic CD4 Lymphocytopenia: Current Insights.ImmunoTargets and therapy · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rajeswari AghoramDepartment of Neurology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), SS Block, D. Nagar, Pondicherry, 605006, India. rajeswari.a@gmail.com.ORCID 0000-0002-4403-4902
Sunil K NarayanDepartment of Neurology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), SS Block, D. Nagar, Pondicherry, 605006, India.
Jawaharlal Institute of Post Graduate Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progressive multifocal leukoencephalopathy is a central nervous system demyelinating disease caused by infection with John Cunningham virus. It affects predominantly the subcortical white matter, producing progressive neurological deficits and large confluent white matter lesions on imaging. It is usually seen in immunodeficient individuals, such as those suffering from acquired immunodeficiency syndrome, those on treatment with monoclonal antibodies, and those following therapeutic bone marrow suppression. Here, we report a rare case of progressive multifocal leukoencephalopathy in an apparently immunocompetent adult, who was found to have idiopathic CD4 lymphocytopenia upon further investigation.

Indexed as

AdultHumansLeukoencephalopathy, Progressive MultifocalMaleT-Lymphocytopenia, Idiopathic CD4-PositiveIdiopathic CD4 lymphocytopeniaProgressive multifocal leukoencephalopathyStrokeTherapy

Identifiers

PMID29687403
OpenAlexW2802259571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.