ArticleAnnals of intensive care2018
Diaphragm function and weaning from mechanical ventilation: an ultrasound and phrenic nerve stimulation clinical study.
Article in Annals of intensive care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04658498 (Improving Our Understanding of Respiratory Muscle Training to Facilitate Weaning From Mechanical Ventilation in the ICU), which is not on this map. Cited by 44 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Improving Our Understanding of Respiratory Muscle Training to Facilitate Weaning From Mechanical Ventilation in the ICU
Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Diagnostic accuracy of lung ultrasound to predict weaning outcome: a systematic review and meta-analysis.Frontiers in medicine · 2024Pooled it
- Diaphragm ultrasound to predict weaning outcome: systematic review and meta-analysis.Anaesthesiology intensive therapy · 2022Pooled it
- Early prediction of noninvasive ventilation failure after extubation: development and validation of a machine-learning model.BMC pulmonary medicine · 2022Trial
- Randomized Clinical Study of Temporary Transvenous Phrenic Nerve Stimulation in Difficult-to-Wean Patients.American journal of respiratory and critical care medicine · 2022Trial
- Neurally adjusted ventilatory assist after surgical treatment of intracerebral hemorrhage: a randomized crossover study.The Journal of international medical research · 2020Trial
- Effects of positive inspiratory and expiratory pressure on diaphragmatic mobility in asymptomatic individuals: Randomised, crossover clinical trial.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao · 2026Article
- Effects of Phrenic Nerve Stimulation in Mechanically Ventilated Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of clinical medicine · 2026Review
- Seeing readiness: a pilot diagnostic accuracy study integrating diaphragm and lung ultrasound to predict extubation outcomes in the NICU.European journal of pediatrics · 2026Article
- A novel methodology for measuring global diaphragm thickness by ultrasonography in patients with critical illness: an exploratory pilot study.BMC medical imaging · 2025Article
- Beyond feasibility: standardization and reproducibility as the next frontier for respiratory muscle ultrasound.Critical care (London, England) · 2025Article
- Advancements in imaging techniques for monitoring the respiratory muscles.Critical care (London, England) · 2025Review
- Predictors of weaning failure in ventilated intensive care patients: a systematic evidence map.Critical care (London, England) · 2024Review
- SARS‑CoV‑2 infection exacerbates diaphragmatic eventration: A case report.Biomedical reports · 2024Article
- Diaphragm muscle parameters as a predictive tool for weaning critically ill patients from mechanical ventilation: a systematic review and meta-analysis study.European journal of translational myology · 2024Article
- Operator independent continuous ultrasound monitoring of diaphragm excursion predicts successful weaning from mechanical ventilation: a prospective observational study.Critical care (London, England) · 2024Observational
- Thoracic ultrasound use in hospitalized and ambulatory adult patients: a quantitative picture.The ultrasound journal · 2024Article
- 2022 Year in Review: Ventilator Liberation.Respiratory care · 2023Review
- Diaphragm function in patients with Covid-19-related acute respiratory distress syndrome on venovenous extracorporeal membrane oxygenation.Annals of intensive care · 2023Article
- Managing respiratory muscle weakness during weaning from invasive ventilation.European respiratory review : an official journal of the European Respiratory Society · 2023Article
- Persistent diaphragm dysfunction after cardiac surgery is associated with adverse respiratory outcomes: a prospective observational ultrasound study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiaphragm dysfunction is defined by a value of twitch tracheal pressure in response to magnetic phrenic stimulation (twitch pressure) amounting to less than 11 cmH
methodsIn patients undergoing a first spontaneous breathing trial, diaphragm function was evaluated by twitch pressure and by diaphragm ultrasound (thickening fraction). Receiver operating characteristics curves were computed to determine the best thresholds predicting failure of spontaneous breathing trial.
resultsSeventy-six patients were evaluated, 48 (63%) succeeded and 28 (37%) failed the spontaneous breathing trial. The optimal thresholds of twitch pressure and thickening fraction to predict failure of the spontaneous breathing trial were, respectively, 7.2 cmH
conclusionsFailure of spontaneous breathing trial can be predicted with a lower value of twitch pressure than the value defining diaphragm dysfunction. Twitch pressure and thickening fraction had similar strong performance in the prediction of failure of the spontaneous breathing trial.
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Registered trials
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