Evidence map›Paper›PMID 29687264›Full record

ArticleEuropean journal of nutrition2019

The association of protein and carbohydrate intake with successful aging: a combined analysis of two epidemiological studies.

Alexandra Foscolou, Emmanuela Magriplis, Stefanos Tyrovolas, Christina Chrysohoou, Labros Sidossis, Antonia-Leda Matalas, Loukianos Rallidis, Demosthenes Panagiotakos

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in European journal of nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
  2. Dietary n-3 Polyunsaturated Fatty Acids From Fish Are Associated With Better Healthy Aging Indicators: Results of the DIAPELH Study.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
    Article
  3. Article
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  9. Effects of Health-Related Behaviors and Changes on Successful Aging among Indonesian Older People.International journal of environmental research and public health · 2022
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Alexandra FoscolouDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Kallithea, Attica, 17671, Athens, Greece.
Emmanuela MagriplisDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Kallithea, Attica, 17671, Athens, Greece.
Stefanos TyrovolasDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Kallithea, Attica, 17671, Athens, Greece.
Christina ChrysohoouFirst Cardiology Clinic, School of Medicine, University of Athens, Athens, Greece.
Labros SidossisDepartment of Kinesiology and Health, School of Arts and Sciences, Rutgers University, New Brunswick, NJ, USA.
Antonia-Leda MatalasDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Kallithea, Attica, 17671, Athens, Greece.
Loukianos RallidisSecond Cardiology Clinic, School of Medicine, University of Athens, Athens, Greece.
Demosthenes PanagiotakosDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Kallithea, Attica, 17671, Athens, Greece. dbpanag@hua.gr.ORCID http://orcid.org/0000-0001-8583-153X
Harokopio University of Athens · GRNational and Kapodistrian University of Athens · GRRutgers, The State University of New Jersey · US

Funding

European Union's Horizon 2020 635316Instituto de Salud Carlos III CD15/00019
6 · The paper itself

Abstract

purposePrevious studies have reported associations between levels of protein and carbohydrate intake with several health outcomes. Yet, their effect on successful (or healthy) aging remains unknown. The purpose of the present work was to investigate the association of protein and carbohydrate intake levels with successful aging.

methodsA cross-sectional analysis was carried out on the participants of two epidemiological studies; the ATTICA and the MEDIS studies. Anthropometrical, clinical and socio-demographic characteristics, dietary habits, and lifestyle parameters were derived through standard procedures. Successful aging was evaluated using a validated index (SAI) composed of 10 health-related social, lifestyle and clinical characteristics.

resultsSAI levels were lower in low protein-high carbohydrate diet group (B = - 0.08, p = 0.04), but higher in high protein-high carbohydrate group (B = 0.06, p = 0.04), as compared to low protein and low carbohydrate diet, in participants living in insular areas. Protein-carbohydrate diet was not associated with SAI (all p's > 0.05) among participants living in urban areas (p for diet-study interaction < 0.001).

conclusionsA high protein diet seems to be beneficial for older islanders in terms of successful aging; stating a hypothesis for a potential diet-environmental interaction that may be related to the quality of foods consumed and, consequently the sources of nutrients.

Indexed as

Health StatusAgedAgingCross-Sectional StudiesDietary CarbohydratesDietary ProteinsFeeding BehaviorFemaleGreeceHealth BehaviorHumansLife StyleMaleMiddle AgedSocial BehaviorDietary CarbohydratesDietary ProteinsCarbohydrateLifestyleNutritionProteinSuccessful aging

Identifiers

PMID29687264
OpenAlexW2799314131

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.