Evidence map›Paper›PMID 29687044›Full record

ArticleTemperature (Austin, Tex.)2018

Estradiol alters body temperature regulation in the female mouse.

Sally J Krajewski-Hall, Elise M Blackmore, Jessi R McMinn, Naomi E Rance

Open access · bronzeAbstract read
In one paragraph

Article in Temperature (Austin, Tex.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 37 citations in OpenAlex.

  1. Trial
  2. Pregnancy damps thermoregulatory rhythms across timescales through neural estrogen signaling in mice.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Sex-specific thermoregulatory effects of estrogen signaling inbioRxiv : the preprint server for biology · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. The novel estrogen receptor beta agonist EGX358 andFrontiers in aging neuroscience · 2024
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sally J Krajewski-HallDepartments of Pathology (S.J.K-H., E.M.B., J.R.M. and N.E.R.), Cellular and Molecular Medicine (N.E.R.), Neurology (N.E.R.) and the Evelyn F. McKnight Brain Institute (N.E.R.) University of Arizona College of Medicine, Tucson, AZ, USA.
Elise M BlackmoreDepartments of Pathology (S.J.K-H., E.M.B., J.R.M. and N.E.R.), Cellular and Molecular Medicine (N.E.R.), Neurology (N.E.R.) and the Evelyn F. McKnight Brain Institute (N.E.R.) University of Arizona College of Medicine, Tucson, AZ, USA.
Jessi R McMinnDepartments of Pathology (S.J.K-H., E.M.B., J.R.M. and N.E.R.), Cellular and Molecular Medicine (N.E.R.), Neurology (N.E.R.) and the Evelyn F. McKnight Brain Institute (N.E.R.) University of Arizona College of Medicine, Tucson, AZ, USA.
Naomi E RanceDepartments of Pathology (S.J.K-H., E.M.B., J.R.M. and N.E.R.), Cellular and Molecular Medicine (N.E.R.), Neurology (N.E.R.) and the Evelyn F. McKnight Brain Institute (N.E.R.) University of Arizona College of Medicine, Tucson, AZ, USA.
University of Arizona · US

Funding

Role of preoptic NK3R neurons in the estrogen modulation of body temperatureR01AG047887 · NIA · UNIVERSITY OF ARIZONA · PI RANCE, NAOMI E · 2014 to 2018
$1.5M
NIA NIH HHS R01 AG047887
6 · The paper itself

Abstract

Hot flushes are due to estrogen withdrawal and characterized by the episodic activation of heat dissipation effectors. Recent studies (in humans and rats) have implicated neurokinin 3 (NK

Indexed as

estrogenhot flushkisspeptinmenopauseneurokinin Bvasodilation

Identifiers

PMID29687044
PMCPMC5902204
OpenAlexW2762720931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.