Evidence map›Paper›PMID 29687042›Full record

ReviewTemperature (Austin, Tex.)2018

Tissue oxidative metabolism can increase the difference between local temperature and arterial blood temperature by up to 1.3

Dmitry V Zaretsky, Andrej A Romanovsky, Maria V Zaretskaia, Yaroslav I Molkov

Open access · bronzeAbstract readReview
In one paragraph

Review in Temperature (Austin, Tex.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Body Temperature Regulation in the Rat by Muscle Tone.Acta physiologica (Oxford, England) · 2026
    Article
  2. Article
  3. Review
  4. Measuring Skeletal Muscle Thermogenesis in Mice and Rats.Journal of visualized experiments : JoVE · 2022
    Article
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Dmitry V ZaretskyDiscovery and Translational Medicine Division, Intarcia Therapeutics, Research Triangle, NC 27709.ORCID 0000-0003-2454-8620
Andrej A RomanovskySystemic Inflammation Laboratory (FeverLab), Trauma Research, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013.
Maria V ZaretskaiaDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN 46202.
Yaroslav I MolkovDepartment of Mathematics and Statistics and Neuroscience Institute, Georgia State University, GA 30303.ORCID 0000-0002-0862-1974
Georgia State University · USIndiana University School of MedicineSt. Joseph's Hospital and Medical Center · USTriangle · US

Funding

Modeling Brainstem Inflammation's Role in Systemic Dysfunction during SepsisU01EB021960 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI DICK, THOMAS E · 2017 to 2020
$2.6M
NIBIB NIH HHS U01 EB021960
6 · The paper itself

Abstract

Tissue temperature increases, when oxidative metabolism is boosted. The source of nutrients and oxygen for this metabolism is the blood. The blood also cools down the tissue, and this is the only cooling mechanism, when direct dissipation of heat from the tissue to the environment is insignificant,

Indexed as

blood flowBody temperaturebrainbrown adipose tissuebrown fatheat dissipationmetabolismmodelingoxygen consumptionthermogenesistissue temperature

Identifiers

PMID29687042
PMCPMC5902193
OpenAlexW2790999138

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.