Evidence map›Paper›PMID 29687028›Full record

ArticleAnnals of clinical and translational neurology2018

Deep cerebral vein expansion with metabolic and neurocognitive recovery in Sturge-Weber syndrome.

Flóra John, Mohsin Maqbool, Jeong-Won Jeong, Rajkumar Agarwal, Michael E Behen, Csaba Juhász

Open access · goldAbstract readCase Reports
In one paragraph

Article in Annals of clinical and translational neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Flóra JohnDepartments of Pediatrics and Neurology Wayne State University School of Medicine Children's Hospital of Michigan Detroit Medical Center Detroit Michigan.
Mohsin MaqboolTexas Child Neurology Plano Texas.
Jeong-Won JeongDepartments of Pediatrics and Neurology Wayne State University School of Medicine Children's Hospital of Michigan Detroit Medical Center Detroit Michigan.
Rajkumar AgarwalDepartments of Pediatrics and Neurology Wayne State University School of Medicine Children's Hospital of Michigan Detroit Medical Center Detroit Michigan.
Michael E BehenDepartments of Pediatrics and Neurology Wayne State University School of Medicine Children's Hospital of Michigan Detroit Medical Center Detroit Michigan.
Csaba JuhászDepartments of Pediatrics and Neurology Wayne State University School of Medicine Children's Hospital of Michigan Detroit Medical Center Detroit Michigan.ORCID 0000-0002-5067-5554
Wayne State University · USPlano Cancer Institute · US

Funding

Longitudinal Neuroimaging in Sturge-Weber SyndromeR01NS041922 · NINDS · WAYNE STATE UNIVERSITY · PI JUHASZ, CSABA · 2003 to 2024
$6.2M
Novel DWI Methods to Minimize Postoperative Deficits in Pediatric Epilepsy Surgery.R01NS089659 · NINDS · WAYNE STATE UNIVERSITY · PI JEONG, JEONG-WON · 2015 to 2025
$3.7M
NINDS NIH HHS R01 NS041922NINDS NIH HHS R01 NS089659
6 · The paper itself

Abstract

We present longitudinal imaging data of a child with Sturge-Weber syndrome (SWS). At age 8 months, 3 weeks after initial seizures and prolonged motor deficit, MRI showed extensive right hemispheric SWS involvement with severe glucose hypometabolism on PET. She was treated with levetiracetam and aspirin. Follow-up imaging at age 29 months showed a robust interval expansion of enlarged deep medullary veins throughout the affected hemisphere along with a dramatic recovery of hemispheric metabolism and normalized neurocognitive functioning. These findings demonstrate a robust, multilobar hemispheric remodeling of deep venous collaterals that likely contributed to reversal of initial metabolic and neurocognitive deficits.

Identifiers

PMID29687028
PMCPMC5899918
OpenAlexW2791101442

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.