Evidence map›Paper›PMID 29687004›Full record

ArticleBioMed research international2018

Efficacy of Stereotactic Body Radiotherapy for Recurrent or Residual Hepatocellular Carcinoma after Transcatheter Arterial Chemoembolization.

Erhua Yao, Jinghong Chen, Xiaofang Zhao, Yinyan Zheng, Xianheng Wu, Fei Han, Hecheng Huang, Ping Liang, Jianmin Liu, Fasheng Wu and 1 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Erhua YaoDepartment of Radiation Oncology, Affiliated Shantou Hospital of Sun Yat-sen University, Shantou, Guangdong 515031, China.
Jinghong ChenShantou Center for Disease Control and Prevention, Shantou, Guangdong 515041, China.ORCID 0000-0002-1764-4748
Xiaofang ZhaoInfectious Diseases Laboratory, Ruikang Hospital, Guangxi Traditional Chinese Medical University, Nanning, Guangxi Zhuang Autonomous Region 530001, China.
Yinyan ZhengDepartment of Preventive Health, Affiliated Shantou Hospital of Sun Yat-sen University, 114 Waima Road, Shantou, Guangdong 515031, China.
Xianheng WuDepartment of Medical Imaging, Affiliated Shantou Hospital of Sun Yat-sen University, Shantou, Guangdong 515031, China.
Fei HanDepartment of Radiation Oncology, Ruikang Hospital, Guangxi Traditional Chinese Medical University, Nanning, Guangxi Zhuang, China.
Hecheng HuangDepartment of Radiation Oncology, Affiliated Shantou Hospital of Sun Yat-sen University, Shantou, Guangdong 515031, China.
Ping LiangDepartment of Radiation Oncology, Ruikang Hospital, Guangxi Traditional Chinese Medical University, Nanning, Guangxi Zhuang, China.
Jianmin LiuDepartment of Radiation Oncology, Ruikang Hospital, Guangxi Traditional Chinese Medical University, Nanning, Guangxi Zhuang, China.
Fasheng WuDepartment of Radiation Oncology, Ruikang Hospital, Guangxi Traditional Chinese Medical University, Nanning, Guangxi Zhuang, China.
Lianxing LinDepartment of Radiation Oncology, Affiliated Shantou Hospital of Sun Yat-sen University, Shantou, Guangdong 515031, China.ORCID 0000-0003-2461-6670
Guangxi University of Chinese Medicine · CNSun Yat-sen University · CNShantou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the efficacy and toxicity of hypofractionated stereotactic body radiotherapy (SBRT) for patients with recurrent or residual hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE).

methodsBetween June 2008 and July 2015, thirty-three patients with HCC were treated by SBRT. There were 63 lesions in 33 patients. A total dose of 39-45 Gy/3-5 fractions was delivered to the 70-80% isodose line.

resultsObjective response rate (CR + PR) was 84.8% at 6 months. The overall survival rate was 87.9%, 75.8%, 57.6%, and 45.5% at 6, 12, 18, and 24 months, respectively. Median overall survival was 19 months. At 3 months, AFP decreased by more than 75% in 51.5% of patients (17/33). Overall survival was significantly different (

conclusionSBRT is a promising noninvasive and palliative treatment with acceptable toxicity for recurrent or residual HCC after TACE.

Indexed as

AdultAgedCarcinoma, HepatocellularChemoembolization, TherapeuticCombined Modality TherapyFemaleHumansLiver NeoplasmsMaleMiddle AgedRadiosurgeryRetrospective StudiesSurvival RateTreatment Outcome

Identifiers

PMID29687004
PMCPMC5857336
OpenAlexW2792368366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.