Evidence map›Paper›PMID 29686991›Full record

ArticleFrontiers in molecular biosciences2018

Metabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice.

Dorsa Varshavi, Flora H Scott, Dorna Varshavi, Sunil Veeravalli, Ian R Phillips, Kirill Veselkov, Nicole Strittmatter, Zoltan Takats, Elizabeth A Shephard, Jeremy R Everett

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Phenotypic and metabonomics studies of FMOs in C. elegans and their roles in lifespan extension.Metabolomics : Official journal of the Metabolomic Society · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Metabolomics to Study Human Aging: A Review.Current molecular medicine · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Dorsa VarshaviMedway Metabonomics Research Group, University of Greenwich, Chatham, United Kingdom.
Flora H ScottInstitute of Structural and Molecular Biology, University College London, London, United Kingdom.
Dorna VarshaviMedway Metabonomics Research Group, University of Greenwich, Chatham, United Kingdom.
Sunil VeeravalliInstitute of Structural and Molecular Biology, University College London, London, United Kingdom.
Ian R PhillipsInstitute of Structural and Molecular Biology, University College London, London, United Kingdom.
Kirill VeselkovDepartment of Surgery and Cancer, Faculty of Medicine, Imperial College, London, United Kingdom.
Nicole StrittmatterDepartment of Surgery and Cancer, Faculty of Medicine, Imperial College, London, United Kingdom.
Zoltan TakatsDepartment of Surgery and Cancer, Faculty of Medicine, Imperial College, London, United Kingdom.
Elizabeth A ShephardInstitute of Structural and Molecular Biology, University College London, London, United Kingdom.
Jeremy R EverettMedway Metabonomics Research Group, University of Greenwich, Chatham, United Kingdom.
Imperial College London · GBInstitute of Structural and Molecular Biology · GBUniversity of Greenwich · GBUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It was recently demonstrated in mice that knockout of the flavin-containing monooxygenase 5 gene,

Indexed as

6-hydroxy-6-methyl-heptan-3-oneageingC57BL/6JFMO5 KOmetabolomicsmetabonomicsplasmaurine

Identifiers

PMID29686991
PMCPMC5900034
OpenAlexW2796532484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.