Evidence map›Paper›PMID 29686839›Full record

ArticleEcology and evolution2018

Signatures of competition and strain structure within the major blood-stage antigen of

Mary M Rorick, Yael Artzy-Randrup, Shazia Ruybal-Pesántez, Kathryn E Tiedje, Thomas S Rask, Abraham Oduro, Anita Ghansah, Kwadwo Koram, Karen P Day, Mercedes Pascual

Abstract read
In one paragraph

Article in Ecology and evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mary M RorickDepartment of Ecology and Evolution University of Chicago Chicago IL USA.ORCID 0000-0001-5495-0472
Yael Artzy-RandrupTheoretical Ecology Group Institute for Biodiversity and Ecosystem Dynamics University of Amsterdam Amsterdam The Netherlands.
Shazia Ruybal-PesántezSchool of Biosciences Bio21 Institute The University of Melbourne Melbourne Vic. Australia.
Kathryn E TiedjeSchool of Biosciences Bio21 Institute The University of Melbourne Melbourne Vic. Australia.
Thomas S RaskSchool of Biosciences Bio21 Institute The University of Melbourne Melbourne Vic. Australia.
Abraham OduroNavrongo Health Research Center Navrongo Ghana.
Anita GhansahNoguchi Memorial Institute for Medical Research University of Ghana Legon Ghana.
Kwadwo KoramNoguchi Memorial Institute for Medical Research University of Ghana Legon Ghana.
Karen P DaySchool of Biosciences Bio21 Institute The University of Melbourne Melbourne Vic. Australia.
Mercedes PascualDepartment of Ecology and Evolution University of Chicago Chicago IL USA.

Funding

P.falciparum var gene diversity and malaria controlR01AI084156 · NIAID · UNIVERSITY OF MELBOURNE · PI DAY, KAREN PATRICIA · 2010 to 2014
$1.9M
The impact of seasonality and vector control on the population structure of Plasmodium falciparumR01TW009670 · FIC · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAY, KAREN PATRICIA, KORAM, KWADWO ANSAH · 2013 to 2016
$1.8M
FIC NIH HHS R01 TW009670NIAID NIH HHS R01 AI084156
6 · The paper itself

Abstract

The concept of niche partitioning has received considerable theoretical attention at the interface of ecology and evolution of infectious diseases. Strain theory postulates that pathogen populations can be structured into distinct nonoverlapping strains by frequency-dependent selection in response to intraspecific competition for host immune space. The malaria parasite

Indexed as

antigenic diversitymodularityniche partitioningPfEMP1strain theoryvar gene

Identifiers

PMID29686839
PMCPMC5901166

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.