ArticleEuropean journal of translational myology2018
Two years of Functional Electrical Stimulation by large surface electrodes for denervated muscles improve skin epidermis in SCI.
Article in European journal of translational myology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Electrical Stimulation of Denervated Muscle: A Narrative Review.Artificial organs · 2026Review
- Electrical stimulation of injured nerves promotes recovery in animals and humans.The Journal of physiology · 2025Review
- Trauma of Peripheral Innervation Impairs Content of Epidermal Langerhans Cells.Diagnostics (Basel, Switzerland) · 2022Article
- SKP-SC-EVs Mitigate Denervated Muscle Atrophy by Inhibiting Oxidative Stress and Inflammation and Improving Microcirculation.Antioxidants (Basel, Switzerland) · 2021Article
- Selective Surface Electrostimulation of the Denervated Zygomaticus Muscle.Diagnostics (Basel, Switzerland) · 2021Article
- Collection of the Abstracts of the 2019Sp PMD: Translational Myology and Mobility Medicine.European journal of translational myology · 2019Article
- Investigation of Iranian pomegranate cultivars for wound healing components.European journal of translational myology · 2019Article
- Myokines in Home-Based Functional Electrical Stimulation-Induced Recovery of Skeletal Muscle in Elderly and Permanent Denervation.European journal of translational myology · 2018Article
- Dermal papillae flattening of thigh skin inEuropean journal of translational myology · 2018Article
- The duty cycle in Functional Electrical Stimulation research. Part II: Duty cycle multiplicity and domain reporting.European journal of translational myology · 2018Article
- Physiological electric field works via the VEGF receptor to stimulate neovessel formation of vascular endothelial cells in a 3D environment.Biology open · 2018Article
- EJTM3 is also covering Mobility and Medicine at large, an update.European journal of translational myology · 2018Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our previous studies have shown that severely atrophic Quadriceps muscles of spinal cord injury (SCI) patients suffering with complete conus and cauda equina lesions, and thus with permanent denervation-induced atrophy and degeneration of muscle fibers, were almost completely rescued to normal size after two years of home-based Functional Electrical Stimulation (h-bFES). Since we used large surface electrodes to stimulate the thigh muscles, we wanted to know if the skin was affected by long-term treatment. Here we report preliminary data of morphometry of skin biopsies harvested from legs of 3 SCI patients before and after two years of h-bFES to determine the total area of epidermis in transverse skin sections. By this approach we support our recently published results obtained randomly measuring skin thickness in the same biopsies after H-E stain. The skin biopsies data of three subjects, taken together, present indeed a statistically significant 30% increase in the area of the epidermis after two years of h-bFES. In conclusion, we confirm a long term positive modulation of electrostimulated epidermis, that correlates with the impressive improvements of the FES-induced muscle strength and bulk, and of the size of the muscle fibers after 2-years of h-bFES.
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