Evidence map›Paper›PMID 29686741›Full record

ArticleCanadian respiratory journal2018

Endobronchial Ultrasound Transbronchial Needle Aspiration in Thoracic Diseases: Much More than Mediastinal Staging.

Juliana Guarize, Monica Casiraghi, Stefano Donghi, Cristina Diotti, Nicolo Vanoni, Rosalia Romano, Chiara Casadio, Daniela Brambilla, Patrick Maisonneuve, Francesco Petrella and 1 more

Open access · goldAbstract read
In one paragraph

Article in Canadian respiratory journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 40 citations in OpenAlex.

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  17. Frontiers in oncology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Juliana GuarizeDivision of Thoracic Surgery, European Institute of Oncology, Milan, Italy.ORCID 0000-0002-1695-1375
Monica CasiraghiDivision of Thoracic Surgery, European Institute of Oncology, Milan, Italy.
Stefano DonghiDivision of Thoracic Surgery, European Institute of Oncology, Milan, Italy.
Cristina DiottiDivision of Thoracic Surgery, European Institute of Oncology, Milan, Italy.
Nicolo VanoniDivision of Thoracic Surgery, European Institute of Oncology, Milan, Italy.
Rosalia RomanoDivision of Thoracic Surgery, European Institute of Oncology, Milan, Italy.
Chiara CasadioDivision of Pathology, European Institute of Oncology, Milan, Italy.
Daniela BrambillaDivision of Thoracic Surgery, European Institute of Oncology, Milan, Italy.
Patrick MaisonneuveDivision of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy.
Francesco PetrellaDivision of Thoracic Surgery, European Institute of Oncology, Milan, Italy.
Lorenzo SpaggiariDivision of Thoracic Surgery, European Institute of Oncology, Milan, Italy.
European Institute of Oncology · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objective: EBUS-TBNA has revolutionized the diagnostic approach to thoracic diseases from a surgical to minimally invasive procedure. In non small-cell lung cancer (NCSLC) patients, EBUS-TBNA is able to dictate the consecutive therapy both for early and advanced stages, providing pathological diagnosis, mediastinal staging, and even adequate specimens for molecular analysis. This study reports on the ability of EBUS-TBNA to make different diagnoses and dictates the consecutive therapy in a large cohort of patients presenting different thoracic diseases. Methods: All procedures performed from January 2012 to September 2016 were reviewed. Five groups of patients were created according to the main indications for the procedure. Group 1: lung cancer staging; Group 2: pathological diagnosis in advanced stage lung cancer; Group 3: lymphadenopathy in previous malignancies; Group 4: pulmonary lesions; Group 5: unknown origin lymphadenopathy. In each group, the diagnostic yield of the procedure was analysed. Non malignant diagnosis at EBUS-TBNA was confirmed by a surgical procedure or clinical and radiological follow-up. Results: 1891 patients were included in the analysis. Sensitivity, negative predictive value, and diagnostic accuracy in each group were 90.7%, 79.4%, and 93.1% in Group 1; 98.5%, 50%, and 98.5% in Group 2; 92.4%, 85.1%, and 94.7% in Group 3; 90.9%, 51.0%, and 91.7% in Group 4; and 25%, 83.3%, and 84.2% in Group 5. Overall sensitivity, negative predictive value, and accuracy were 91.7%, 78.5%, and 93.6%, respectively. Conclusions: EBUS-TBNA is the best approach for invasive mediastinal investigation, confirming its strategic role and high accuracy in thoracic oncology.

Indexed as

AdultAgedAged, 80 and overEndoscopic Ultrasound-Guided Fine Needle AspirationFemaleFollow-Up StudiesHumansLymph NodesMaleMiddle AgedRetrospective StudiesThoracic DiseasesYoung Adult

Identifiers

PMID29686741
PMCPMC5857308
OpenAlexW2789628421

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.