Evidence map›Paper›PMID 29686629›Full record

ArticleFrontiers in psychiatry2018

Critical Role for G

Meridith T Robins, Terrance Chiang, Kendall L Mores, Doungkamol Alongkronrusmee, Richard M van Rijn

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Identification of 1,3,8-Triazaspiro[4.5]Decane-2,4-Dione Derivatives as a NovelThe Journal of pharmacology and experimental therapeutics · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Chemogenetics as a neuromodulatory approach to treating neuropsychiatric diseases and disorders.Molecular therapy : the journal of the American Society of Gene Therapy · 2022
    Review
  8. Characterization of DREADD receptor expression and function in rhesus macaques trained to discriminate ethanol.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Article
  9. Article
  10. Review
  11. Long-Term Depression of Striatal DA Release Induced by mGluRsFrontiers in cellular neuroscience · 2021
    Article
  12. Article
  13. Article
  14. The Meta-Position of PheMolecules (Basel, Switzerland) · 2019
    Article
  15. Review
  16. Rubiscolins are naturally occurring G protein-biased delta opioid receptor peptides.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2019
    Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Meridith T RobinsDepartment of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, United States.
Terrance ChiangDepartment of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, United States.
Kendall L MoresDepartment of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, United States.
Doungkamol AlongkronrusmeeDepartment of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, United States.
Richard M van RijnDepartment of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, United States.
Purdue University West Lafayette · US

Funding

G-protein-, beta-arrestin- and ERK-signaling in alcohol use- and anxiety-disordersR01AA025368 · NIAAA · PURDUE UNIVERSITY · PI CHESTER, JULIA ANN · 2017 to 2021
$1.7M
NIAAA NIH HHS R01 AA025368
6 · The paper itself

Abstract

The transition from non-dependent alcohol use to alcohol dependence involves increased activity of the dorsal striatum. Interestingly, the dorsal striatum expresses a large number of inhibitory G-protein-coupled receptors (GPCRs), which when activated may inhibit alcohol-induced increased activity and can decrease alcohol consumption. Here, we explore the hypothesis that dorsal striatal G

Indexed as

alcohol intakebiased signalingC57BL/6 micedelta-opioid receptordesigner receptors exclusively activated by designer drugsdorsal striatumβ-arrestin

Identifiers

PMID29686629
PMCPMC5900748
OpenAlexW2796182599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.