Evidence map›Paper›PMID 29686623›Full record

ArticleFrontiers in physiology2018

Ticagrelor Improves Endothelial Function by Decreasing Circulating Epidermal Growth Factor (EGF).

Francesco Vieceli Dalla Sega, Francesca Fortini, Giorgio Aquila, Rita Pavasini, Simone Biscaglia, Davide Bernucci, Annamaria Del Franco, Elisabetta Tonet, Paola Rizzo, Roberto Ferrari and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

  1. Ticagrelor IncreasesInternational journal of molecular sciences · 2020
    Trial
  2. Trial
  3. Article
  4. Article
  5. Serum from COVID-19 patients promotes endothelial cell dysfunction through protease-activated receptor 2.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  6. Review
  7. Article
  8. Review
  9. Observational
  10. Review
  11. Pleiotropic Effects of Ticagrelor: Influence onDrug design, development and therapy · 2022
    Article
  12. Review
  13. Review
  14. Beneficial Effects of Ticagrelor on Oxidized Low-Density Lipoprotein (ox-LDL)-Induced Apoptosis in Human Umbilical Vein Endothelial Cells.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Francesco Vieceli Dalla SegaDepartment of Medical Sciences, University of Ferrara, Ferrara, Italy.
Francesca FortiniDepartment of Medical Sciences, University of Ferrara, Ferrara, Italy.
Giorgio AquilaDepartment of Medical Sciences, University of Ferrara, Ferrara, Italy.
Rita PavasiniCardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, Cona, Italy.
Simone BiscagliaCardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, Cona, Italy.
Davide BernucciCardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, Cona, Italy.
Annamaria Del FrancoCardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, Cona, Italy.
Elisabetta TonetCardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, Cona, Italy.
Paola RizzoDepartment of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.
Roberto FerrariMaria Cecilia Hospital, GVM Care & Research, E.S. Health Science Foundation, Cotignola, Italy.
Gianluca CampoDepartment of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.
Arcispedale Sant'Anna · ITUniversity of Ferrara · ITMaria Cecilia Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ticagrelor is one of the most powerful P2Y

Indexed as

chronic obstructive pulmonary disease (COPD)EGFendothelial functioneNOSepidermal growth factor (EGF)stable coronary artery disease (SCAD)ticagrelor

Identifiers

PMID29686623
PMCPMC5900783
OpenAlexW2826748633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.