Evidence map›Paper›PMID 29686516›Full record

ArticleSaudi journal of biological sciences2018

Structural alterations in rat myocardium induced by chronic l-arginine and l-NAME supplementation.

Amal Abdussalam Ali A Hmaid, Milica Markelic, Vesna Otasevic, Sava Masovic, Aleksandra Jankovic, Bato Korac, Aleksandra Korac

Open access · hybridAbstract read
In one paragraph

Article in Saudi journal of biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Chronic aerobic exercise associated to low-dose L-NAME improves contractility without changing calcium handling in rat cardiomyocytes.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2020
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Amal Abdussalam Ali A HmaidChair of Cell and Tissue Biology, Faculty of Biology, University of Belgrade, Studentski trg 16, 11000 Belgrade, Serbia.
Milica MarkelicChair of Cell and Tissue Biology, Faculty of Biology, University of Belgrade, Studentski trg 16, 11000 Belgrade, Serbia.
Vesna OtasevicDepartment of Physiology, Institute for Biological Research "Sinisa Stankovic", University of Belgrade, Bulevar Despota Stefana 142, 11000 Belgrade, Serbia.
Sava MasovicDepartment of Physiology, Institute for Biological Research "Sinisa Stankovic", University of Belgrade, Bulevar Despota Stefana 142, 11000 Belgrade, Serbia.
Aleksandra JankovicDepartment of Physiology, Institute for Biological Research "Sinisa Stankovic", University of Belgrade, Bulevar Despota Stefana 142, 11000 Belgrade, Serbia.
Bato KoracDepartment of Physiology, Institute for Biological Research "Sinisa Stankovic", University of Belgrade, Bulevar Despota Stefana 142, 11000 Belgrade, Serbia.
Aleksandra KoracChair of Cell and Tissue Biology, Faculty of Biology, University of Belgrade, Studentski trg 16, 11000 Belgrade, Serbia.
University of Belgrade · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Structural changes affecting cardiomyocyte function may contribute to the pathophysiological remodeling underlying cardiac function impairment. Recent reports have shown that endogenous nitric oxide (NO) plays an important role in this process. In order to examine the role of NO in cardiomyocyte remodeling, male rats were acclimated to room temperature (22 ± 1 °C) or cold (4 ± 1 °C) and treated with 2.25% l-arginine·HCl or 0.01% l-NAME (N

Indexed as

Cardiac hypertrophyCardiomyocyteeNOS, endothelial NOSiNOS, inducible NOSl-Argininel-NAMEl-NAME, Nω-nitro-l-arginine methyl esterMyocardiumnNOS, neuronal NOSNO, nitric oxideNOS, nitric oxide synthase

Identifiers

PMID29686516
PMCPMC5910630
OpenAlexW2275055654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.