ArticleScientific reports2018
On the role of the prefrontal cortex in fatigue effects on cognitive flexibility - a system neurophysiological approach.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Application of Graph Theory for Identifying Connectivity Patterns in Human Brain Networks: A Systematic Review.Frontiers in neuroscience · 2019Pooled it
- An event-related potential study using a cued task-switching paradigm reveals neural correlates of cognitive flexibility impairments in schizophrenia.BMC psychiatry · 2025Article
- The Role of Sleep Quality and Sleepiness in the Relationship Between Cognitive Flexibility and Fatigue.The Psychiatric quarterly · 2025Article
- A [Journal of neuroinflammation · 2025Article
- Mental fatigue increases perception of effort but does not compromise the inhibitory control of football referees during a match simulation physical task.European journal of sport science · 2025Article
- Neurological mechanisms of mental fatigue in cognitive flexibility in soccer players: an event-related potential study based on N2 components.Frontiers in neuroscience · 2025Article
- Depression and daytime dysfunction centralize the fatigue-sleep cascade in island firefighters: a symptom network and Bayesian DAG study.Frontiers in psychiatry · 2025Article
- Aperiodic neural activity reflects metacontrol in task-switching.Scientific reports · 2024Article
- Double task switching: An investigation into the effects of similarity and task-rule congruency on cognitive flexibility.PloS one · 2024Article
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- Cognitive effects of prolonged continuous human-machine interaction: The case for mental state-based adaptive interfaces.Frontiers in neuroergonomics · 2022Review
- Multi-level decoding of task sets in neurophysiological data during cognitive flexibility.iScience · 2021Article
- The interplay of resting and inhibitory control-related theta-band activity depends on age.Human brain mapping · 2021Article
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- Neurobehavioural complications of sleep deprivation: Shedding light on the emerging role of neuroactive steroids.Journal of neuroendocrinology · 2020Review
Corrections and comments
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3 authors.
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Abstract
Demanding tasks like cognitive flexibility show time-related deterioration of performance (i.e. fatigability effects). Fatigability has been associated with structural and functional properties of the prefrontal cortex. However, the electrophysiological underpinnings of these processes are not well understood. We examined n = 34 healthy participants with a task switching paradigm in which switches were either signaled by cues or needed to be maintained by working memory processes. We analyzed event-related potentials (ERPs) and performed residue iteration decomposition (RIDE) to account for effects of fatigue on intra-individual variability of neurophysiological data. This was combined with source localization methods. We show that task switching is affected by time on task (TOT) effects mostly when working memory processes are needed. On a neurophysiological level, this effect could not be observed in standard ERPs, but only after accounting for intra-individual variability using RIDE. The RIDE data suggests that during task switching, fatigability specifically affects response recoding processes that are associated with functions of the middle frontal gyrus (MFG; BA10). The results underline propositions of the 'opportunity cost model', which states that fatigability effects of executive functions depend on the degree to which tasks engage similar prefrontal regions - in this case working memory and task switching mechanisms.
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