Evidence map›Paper›PMID 29686157›Full record

ArticleAntimicrobial agents and chemotherapy2018

Antimicrobial Activity of Murepavadin Tested against Clinical Isolates of Pseudomonas aeruginosa from the United States, Europe, and China.

Helio S Sader, Glenn E Dale, Paul R Rhomberg, Robert K Flamm

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Lipopolysaccharide-targeting treatments for multidrug-resistantExpert opinion on therapeutic targets · 2026
    Review
  5. Negamycin: Nature's Forgotten Antibiotic.ACS infectious diseases · 2026
    Review
  6. Review
  7. Metallo-β-lactamase-producingFrontiers in microbiology · 2026
    Review
  8. Review
  9. Review
  10. Review
  11. [Clinical characteristics and risk factors of carbapenem-resistantZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Mutations in genesAntimicrobial agents and chemotherapy · 2024
    Article
  17. Article
  18. Review
  19. Age of Antibiotic Resistance in MDR/XDR Clinical Pathogen ofPharmaceuticals (Basel, Switzerland) · 2023
    Review
  20. Anti-Microorganisms · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Helio S SaderJMI Laboratories, North Liberty, Iowa, USA helio-sader@jmilabs.com.
Glenn E DalePolyphor Ltd., Allschwil, Switzerland.
Paul R RhombergJMI Laboratories, North Liberty, Iowa, USA.
Robert K FlammJMI Laboratories, North Liberty, Iowa, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Murepavadin (formerly POL7080), a 14-amino-acid cyclic peptide, and comparators were tested by the broth microdilution method against 1,219

Indexed as

Anti-Bacterial AgentsChinaColistinDrug Resistance, Multiple, BacterialEuropeHumansMicrobial Sensitivity TestsPeptides, CyclicPolymyxin BPseudomonas aeruginosaPseudomonas InfectionsUnited StatesAnti-Bacterial AgentsColistinmurepavadinPeptides, CyclicPolymyxin Bantimicrobial resistanceChinacyclic peptidecyclopeptidemurepavadinPOL7080PolyphorPseudomonas aeruginosa

Identifiers

PMID29686157
PMCPMC6021639

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.