Evidence map›Paper›PMID 29686140›Full record

ArticleJournal of bacteriology2018

Domains within RbpA Serve Specific Functional Roles That Regulate the Expression of Distinct Mycobacterial Gene Subsets.

Jerome Prusa, Drake Jensen, Gustavo Santiago-Collazo, Steven S Pope, Ashley L Garner, Justin J Miller, Ana Ruiz Manzano, Eric A Galburt, Christina L Stallings

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. SigE: A master regulator ofFrontiers in microbiology · 2023
    Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. CarD contributes to diverse gene expression outcomes throughout the genome ofProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  12. The calculation of transcript flux ratios reveals single regulatory mechanisms capable of activation and repression.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jerome PrusaDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Drake JensenDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri, USA.
Gustavo Santiago-CollazoDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Steven S PopeDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Ashley L GarnerDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Justin J MillerDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Ana Ruiz ManzanoDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri, USA.
Eric A GalburtDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri, USA.
Christina L StallingsDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA stallings@wustl.edu.
Washington University in St. Louis · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
TRAINING PROGRAM IN CELLULAR AND MOLECULAR BIOLOGYT32GM007067 · NIGMS · WASHINGTON UNIVERSITY · PI TRUE-KROB, HEATHER L · 1985 to 2020
$20.4M
Infectious Diseases/Basic Microbial Pathogenic MechanismsT32AI007172 · NIAID · WASHINGTON UNIVERSITY · PI Daniel E. Goldberg, JENNIFER A PHILIPS · 1985 to 2026
$13.0M
OPPORTUNITIES IN GENOMICS RESEARCH: INCREASING DIVERSITY AND RETENTION IN STEMR25HG006687 · NHGRI · WASHINGTON UNIVERSITY · PI MITRA, ROBI D, SKEATH, JAMES BENJAMIN · 2012 to 2025
$4.1M
INVESTIGATING NOVEL MECHANISMS OF TRANSCRIPTION INITIATION REGULATION IN MYCOBACTERIAR01GM107544 · NIGMS · WASHINGTON UNIVERSITY · PI GALBURT, ERIC A, STALLINGS, CHRISTINA LEIGH · 2013 to 2017
$1.5M
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NCI NIH HHS P30 CA091842NHGRI NIH HHS R25 HG006687NIAID NIH HHS T32 AI007172NIGMS NIH HHS R01 GM107544NIGMS NIH HHS T32 GM007067
6 · The paper itself

Abstract

The RNA polymerase (RNAP) binding protein A (RbpA) contributes to the formation of stable RNAP-promoter open complexes (RP

Indexed as

Gene Expression Regulation, BacterialBacterial ProteinsDNA-Directed RNA PolymerasesMycobacterium smegmatisMycobacterium tuberculosisPromoter Regions, GeneticProtein DomainsSigma FactorTranscription, GeneticBacterial ProteinsDNA-Directed RNA PolymerasesSigma FactoreubacteriaMycobacteriumRbpARNA polymerasestranscriptiontranscriptional regulation

Identifiers

PMID29686140
PMCPMC5996690
OpenAlexW2802032176

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.