Evidence map›Paper›PMID 29686104›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Interdependent and separable functions of

Chloe Girard, Baptiste Roelens, Karl A Zawadzki, Anne M Villeneuve

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  10. Review
  11. Exploring the Impact ofNutrients · 2023
    Article
  12. Article
  13. Review
  14. Article
  15. Mechanism of mitotic recombination: insights from C. elegans.Current opinion in genetics & development · 2021
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Mechanism and Control of Meiotic DNA Double-Strand Break Formation inFrontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Chloe GirardDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305.ORCID 0000-0002-1459-6226
Baptiste RoelensDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305.
Karl A ZawadzkiDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305.
Anne M VilleneuveDepartment of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305; annev@stanford.edu.
Stanford University · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Meiotic Chromosome Inheritance in C. elegansR35GM126964 · NIGMS · STANFORD UNIVERSITY · PI ANNE M VILLENEUVE · 2018 to 2026
$6.2M
Genetic Recombination of c. ElegansR01GM067268 · NIGMS · STANFORD UNIVERSITY · PI VILLENEUVE, ANNE M · 2003 to 2017
$4.6M
NIGMS NIH HHS R01 GM067268NIGMS NIH HHS R35 GM126964NIH HHS P40 OD010440
6 · The paper itself

Abstract

Faithful inheritance of genetic information through sexual reproduction relies on the formation of crossovers between homologous chromosomes during meiosis, which, in turn, relies on the formation and repair of numerous double-strand breaks (DSBs). As DSBs pose a potential threat to the genome, mechanisms that ensure timely and error-free DSB repair are crucial for successful meiosis. Here, we identify NBS-1, the

Indexed as

DNA Breaks, Double-StrandedDNA End-Joining RepairHomologous RecombinationMeiosisAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsEmbryo, NonmammalianCaenorhabditis elegans ProteinsDNA repairdouble-strand breakshomologous recombinationmeiosisnon-homologous end joining

Identifiers

PMID29686104
PMCPMC5948970
OpenAlexW2765376730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.