Evidence map›Paper›PMID 29686065›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Earth BioGenome Project: Sequencing life for the future of life.

Harris A Lewin, Gene E Robinson, W John Kress, William J Baker, Jonathan Coddington, Keith A Crandall, Richard Durbin, Scott V Edwards, Félix Forest, M Thomas P Gilbert and 14 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 461 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
461citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

461 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Bony fish genomes: Status and gaps.Journal of fish biology · 2026
    Review
  14. Prospects for Complete DNA Barcode Coverage of the New Zealand Insect Fauna.Journal of the Royal Society of New Zealand · 2026
    Article
  15. Article
  16. Review
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401 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Harris A LewinDepartment of Evolution and Ecology, University of California, Davis, CA 95616; Lewin@ucdavis.edu.
Gene E RobinsonCarl R. Woese Institute for Genomic Biology, Department of Entomology, and Neuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
W John KressNational Museum of Natural History, Smithsonian Institution, Washington, DC 20013.
William J BakerRoyal Botanic Gardens, Kew, Richmond, Surrey TW9 3AE, United Kingdom.
Jonathan CoddingtonNational Museum of Natural History, Smithsonian Institution, Washington, DC 20013.
Keith A CrandallComputational Biology Institute, Milken Institute School of Public Health, George Washington University, Washington, DC 20052.ORCID 0000-0002-0836-3389
Richard DurbinDepartment of Genetics, University of Cambridge, Cambridge CB10 1SA, United Kingdom.
Scott V EdwardsDepartment of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138.ORCID 0000-0003-2535-6217
Félix ForestRoyal Botanic Gardens, Kew, Richmond, Surrey TW9 3AE, United Kingdom.
M Thomas P GilbertNatural History Museum of Denmark, University of Copenhagen, 1350 Copenhagen, Denmark.
Melissa M GoldsteinDepartment of Health Policy and Management, Milken Institute School of Public Health, George Washington University, Washington, DC 20052.
Igor V GrigorievUS Department of Energy Joint Genome Institute, Walnut Creek, CA 94598.
Kevin J HackettAgricultural Research Center, US Department of Agriculture, Beltsville, MD 20705.
David HausslerUC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA 95064.
Erich D JarvisLaboratory of Neurogenetics of Language, The Rockefeller University, New York, NY 10065.
Warren E JohnsonConservation Biology Institute, National Zoological Park, Smithsonian Institution, Front Royal, VA 22630.
Aristides PatrinosNovim Group, University of California, Santa Barbara, CA 93106.
Stephen RichardsHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030.
Juan Carlos Castilla-RubioWorld Economic Forum's Global Future Council on Environment and Natural Resource Security, Cologny/Geneva CH-1223, Switzerland.
Marie-Anne van SluysDepartmento de Botanica, Instituto de Biociencia, Universidade de São Paulo, São Paulo, SP 05508-090, Brazil.
Pamela S SoltisFlorida Museum of Natural History, University of Florida, Gainesville, FL 32611.
Xun XuChina National Genebank, BGI-Shenzhen, 518083 Shenzhen, Guangdong, China.
Huanming YangBGI-Shenzhen, 518083 Shenzhen, Guangdong, China.
Guojie ZhangChina National Genebank, BGI-Shenzhen, 518083 Shenzhen, Guangdong, China.

Funding

Howard Hughes Medical InstituteWellcome Trust 207492/Z/17/Z
6 · The paper itself

Abstract

Increasing our understanding of Earth's biodiversity and responsibly stewarding its resources are among the most crucial scientific and social challenges of the new millennium. These challenges require fundamental new knowledge of the organization, evolution, functions, and interactions among millions of the planet's organisms. Herein, we present a perspective on the Earth BioGenome Project (EBP), a moonshot for biology that aims to sequence, catalog, and characterize the genomes of all of Earth's eukaryotic biodiversity over a period of 10 years. The outcomes of the EBP will inform a broad range of major issues facing humanity, such as the impact of climate change on biodiversity, the conservation of endangered species and ecosystems, and the preservation and enhancement of ecosystem services. We describe hurdles that the project faces, including data-sharing policies that ensure a permanent, freely available resource for future scientific discovery while respecting access and benefit sharing guidelines of the Nagoya Protocol. We also describe scientific and organizational challenges in executing such an ambitious project, and the structure proposed to achieve the project's goals. The far-reaching potential benefits of creating an open digital repository of genomic information for life on Earth can be realized only by a coordinated international effort.

Indexed as

BiodiversityEndangered SpeciesGenomeHigh-Throughput Nucleotide SequencingEarth, Planetaccess and benefit sharingbiodiversitydata sciencegenome sequencinggenomics

Identifiers

PMID29686065
PMCPMC5924910

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.