Evidence map›Paper›PMID 29685953›Full record

ArticleBlood advances2018

Outcomes of Medicare-age eligible NHL patients receiving RIC allogeneic transplantation: a CIBMTR analysis.

Nirav N Shah, Kwang Woo Ahn, Carlos Litovich, Timothy S Fenske, Sairah Ahmed, Minoo Battiwalla, Nelli Bejanyan, Parastoo B Dahi, Javier Bolaños-Meade, Andy I Chen and 22 more

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  9. Article
  10. Cellular Immunotherapy for Refractory Diffuse Large B Cell Lymphoma in the Chimeric Antigen Receptor-Engineered T Cell Era: Still a Role for Allogeneic Transplantation?Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2020
    Review
  11. Where does transplant fit in the age of targeted therapies?Hematology. American Society of Hematology. Education Program · 2019
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Novel therapies for relapsed/refractory aggressive lymphomas.Hematology. American Society of Hematology. Education Program · 2018
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors at 20 institutions in 3 countries.

Nirav N ShahDivision of Hematology and Oncology.
Kwang Woo AhnDivision of Biostatistics, Institute for Health and Society.
Carlos LitovichCenter for International Blood and Marrow Transplant Research, Department of Medicine, and.
Timothy S FenskeDivision of Hematology and Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI.
Sairah AhmedMD Anderson Cancer Center, University of Texas, Houston, TX.
Minoo BattiwallaHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Nelli BejanyanDivision of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN.
Parastoo B DahiAdult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Javier Bolaños-MeadeThe Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD.
Andy I ChenOregon Health and Science University, Portland, OR.
Stefan O CiureaMD Anderson Cancer Center, University of Texas, Houston, TX.
Veronika BachanovaBone and Marrow Transplant Program, University of Minnesota Medical Center, Minneapolis, MN.
Zachariah DeFilippBlood and Marrow Transplant Program, Massachusetts General Hospital, Boston, MA.
Narendranath EpperlaDivision of Hematology, The James Cancer Center and Solove Research Institute, The Ohio State University, Columbus, OH.
Nosha FarhadfarUniversity of Florida, Gainesville, FL.
Alex F HerreraCity of Hope, Duarte, CA.
Bradley M HaverkosUniversity of Colorado Hospital, Aurora, CO.
Leona HolmbergFred Hutchinson Cancer Research Center, Seattle, WA.
Nasheed M HossainDivision of Blood and Marrow Transplantation, Stanford University School of Medicine, Stanford, CA.
Mohamed A Kharfan-DabajaBlood and Marrow Transplantation Program, Division of Hematology-Oncology, Mayo Clinic, Jacksonville, FL.
Vaishalee P KenkreUniversity of Wisconsin, Madison, WI.
Hillard M LazarusSeidman Cancer Center, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, OH.
Hemant S MurthyUniversity of Florida, Gainesville, FL.
Taiga NishihoriDepartment of Blood and Marrow Transplant and Cellular Immunotherapy, H. Lee Moffitt Cancer Center, Tampa, FL.
Andrew R RezvaniDivision of Blood and Marrow Transplantation, Stanford University School of Medicine, Stanford, CA.
Anita D'SouzaCenter for International Blood and Marrow Transplant Research, Department of Medicine, and.
Bipin N SavaniDivision of Hematology/Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.
Matthew L UlricksonBanner MD Anderson Cancer Center, Gilbert, AZ.
Edmund K WallerDepartment of Hematology and Oncology, Winship Cancer Institute, Emory University, Atlanta, GA.
Anna SuredaHematology Department, Institut Català d'Oncologia-Hospitalet, Barcelona, Spain; and.
Sonali M SmithSection of Hematology/Oncology, The University of Chicago, Chicago, IL.
Mehdi HamadaniCenter for International Blood and Marrow Transplant Research, Department of Medicine, and.
Stanford University · USThe University of Texas MD Anderson Cancer Center · USUniversity of Florida · USBanner MD Anderson Cancer CenterCase Western Reserve University · USCity of Hope · USEmory University · USFred Hutch Cancer Center · USInstitut Català d'Oncologia · ESInstitute for Medical Informatics and Biostatistics · CHMassachusetts General Hospital · USMayo Clinic in Florida · USMedical College of Wisconsin · USMemorial Sloan Kettering Cancer Center · USMoffitt Cancer Center · USNational Institutes of Health · USOregon Health & Science University · USPalmetto Hematology Oncology · USSidney Kimmel Comprehensive Cancer Center · USThe Ohio State University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Data Resource for Analyzing Blood &Marrow TransplantsU24CA076518 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Amy M Moskop, Bronwen Shaw · 1998 to 2026
$105.2M
Easy-to-read Informed Consent for HCT Clinical TrialsU10HL069294 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HOROWITZ, MARY MARESCA · 2011 to 2016
$43.8M
NCI NIH HHS P30 CA008748NCI NIH HHS U24 CA076518NHLBI NIH HHS U10 HL069294
6 · The paper itself

Abstract

The application of allogeneic hematopoietic cell transplantation (allo-HCT) in non-Hodgkin lymphoma (NHL) patients ≥65 years in the United States is limited by lack of Medicare coverage for this indication. Using the Center for International Blood and Marrow Transplant Research (CIBMTR) database, we report allo-HCT outcomes of NHL patients aged ≥65 years (older cohort; n = 446) compared with a cohort of younger NHL patients aged 55-64 years (n = 1183). We identified 1629 NHL patients undergoing a first reduced-intensity conditioning (RIC) or nonmyeloablative conditioning allo-HCT from 2008 to 2015 in the United States. Cord blood or haploidentical transplants were excluded. The median age was 68 years (range 65-77) for the older cohort vs 60 years (range 55-64) in the younger cohort. The 4-year adjusted probabilities of nonrelapse mortality (NRM), relapse/progression (R/P), progression-free survival (PFS), and overall survival (OS) of the younger and older groups were 24% vs 30% (

Indexed as

AgedAge FactorsDatabases, FactualHematopoietic Stem Cell TransplantationHumansLymphoma, Non-HodgkinMedicareMiddle AgedSurvival AnalysisTransplantation ConditioningTransplantation, HomologousUnited States

Identifiers

PMID29685953
PMCPMC5916010
OpenAlexW2799756006

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.