Observational studyCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2018
Recent opioid use and fall-related injury among older patients with trauma.
Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph
Observational study in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
16.3field-weighted citation impact, top 1% of its field
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.
- Potential for Harm Associated with Discharge Opioids After Hospital Stay: A Systematic Review.Drugs · 2020Pooled it
- Preoperative Quadratus Lumborum Block Reduces Opioid Requirements in the Immediate Postoperative Period Following Hip Arthroscopy: A Randomized, Blinded Clinical Trial.Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association · 2022Trial
- National Trends In US Opioid-Related Hospitalizations, 2016-23.Health affairs (Project Hope) · 2026Article
- Risk of hospitalization and opioid use in older people with dementia.BMC geriatrics · 2026Article
- Preliminary Evidence Supporting Validity and Reliability of the Assessment for Appropriate Use of Opioids for Long-Term Care.The Senior care pharmacist · 2025Article
- Association between timing of surgery and refracture after initial osteoporotic fractures.Scientific reports · 2025Article
- A descriptive analysis of rural seniors with femur and pelvis fractures and the impact of morphine milliequivalents on inpatient rehabilitation.Journal of family medicine and primary care · 2025Article
- An Overview of Opioid Prescription Patterns among Non-Opioid Users Following Emergency Department Admission.Healthcare (Basel, Switzerland) · 2024Article
- Observational
- Association of Primary Care Risk Mitigation Visits and Nonelective Emergency Department Visits in Patients Using Long-term Opioid Therapy.Mayo Clinic proceedings. Innovations, quality & outcomes · 2023Article
- Impact of substance-related harms on injury hospitalizations in Canada, from 2010 to 2020.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2023Article
- Australian emergency department care for older adults diagnosed with low back pain of lumbar spine origin: a retrospective analysis of electronic medical record system data (2016-2019).BMC emergency medicine · 2023Article
- Opioid use for a first-incident upper extremity fracture in 220,440 patients without recent prior use in Ontario, Canada: a retrospective cohort study.OTA international : the open access journal of orthopaedic trauma · 2022Article
- Article
- Averting a UK opioid crisis: getting the public health messages 'right'.Journal of the Royal Society of Medicine · 2022Article
- Pain management in emergency department older adults with pelvic fracture: still insufficient.CJEM · 2022Article
- Pain and Prescription Opioid Use Among US Construction Workers: Findings From the 2011‒2018 Medical Expenditure Panel Survey.American journal of public health · 2022Article
- Article
- Opioid prescribing in out-of-hours primary care in Flanders and the Netherlands: A retrospective cross-sectional study.PloS one · 2022Article
- Patterns of pre-operative opioid use affect the risk for complications after total joint replacement.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Raoul DaoustDepartment of Emergency Medicine (Daoust, Paquet, Chauny), Research Centre, Hôpital du Sacré-Coeur de Montréal; Faculté de Médecine (Daoust, Mac-Thiong, Chauny), Université de Montréal; Montréal, Que.; Département de médecine sociale et préventive (Moore), Faculté de médecine, Université Laval; Axe de recherche en traumatologie-urgence-soins intensifs du Centre de recherche FRQS du CHU-Québec (Moore); Département de médecine familiale et de médecine d'urgence (Émond), Faculté de médecine, Université Laval, Québec, Que.; Department of Emergency Medicine (Gosselin), McGill University Health Centre, McGill University; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal; Center for Advanced Research in Sleep Medicine (Lavigne), Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord de-l'Île-de-Montréal); Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM) (Choinière, Boulanger); Département d'anesthésiologie (Choinière), Faculté de médecine, Université de Montréal; Research Centre (Daoust, Paquet, Mac-Thiong, Chauny), Hôpital du Sacré-Coeur (CIUSSS du Nord de-l'Île-de-Montréal), Montréal, Que. raoul.daoust@videotron.ca.
Jean PaquetDepartment of Emergency Medicine (Daoust, Paquet, Chauny), Research Centre, Hôpital du Sacré-Coeur de Montréal; Faculté de Médecine (Daoust, Mac-Thiong, Chauny), Université de Montréal; Montréal, Que.; Département de médecine sociale et préventive (Moore), Faculté de médecine, Université Laval; Axe de recherche en traumatologie-urgence-soins intensifs du Centre de recherche FRQS du CHU-Québec (Moore); Département de médecine familiale et de médecine d'urgence (Émond), Faculté de médecine, Université Laval, Québec, Que.; Department of Emergency Medicine (Gosselin), McGill University Health Centre, McGill University; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal; Center for Advanced Research in Sleep Medicine (Lavigne), Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord de-l'Île-de-Montréal); Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM) (Choinière, Boulanger); Département d'anesthésiologie (Choinière), Faculté de médecine, Université de Montréal; Research Centre (Daoust, Paquet, Mac-Thiong, Chauny), Hôpital du Sacré-Coeur (CIUSSS du Nord de-l'Île-de-Montréal), Montréal, Que.
Lynne MooreDepartment of Emergency Medicine (Daoust, Paquet, Chauny), Research Centre, Hôpital du Sacré-Coeur de Montréal; Faculté de Médecine (Daoust, Mac-Thiong, Chauny), Université de Montréal; Montréal, Que.; Département de médecine sociale et préventive (Moore), Faculté de médecine, Université Laval; Axe de recherche en traumatologie-urgence-soins intensifs du Centre de recherche FRQS du CHU-Québec (Moore); Département de médecine familiale et de médecine d'urgence (Émond), Faculté de médecine, Université Laval, Québec, Que.; Department of Emergency Medicine (Gosselin), McGill University Health Centre, McGill University; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal; Center for Advanced Research in Sleep Medicine (Lavigne), Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord de-l'Île-de-Montréal); Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM) (Choinière, Boulanger); Département d'anesthésiologie (Choinière), Faculté de médecine, Université de Montréal; Research Centre (Daoust, Paquet, Mac-Thiong, Chauny), Hôpital du Sacré-Coeur (CIUSSS du Nord de-l'Île-de-Montréal), Montréal, Que.
Marcel ÉmondDepartment of Emergency Medicine (Daoust, Paquet, Chauny), Research Centre, Hôpital du Sacré-Coeur de Montréal; Faculté de Médecine (Daoust, Mac-Thiong, Chauny), Université de Montréal; Montréal, Que.; Département de médecine sociale et préventive (Moore), Faculté de médecine, Université Laval; Axe de recherche en traumatologie-urgence-soins intensifs du Centre de recherche FRQS du CHU-Québec (Moore); Département de médecine familiale et de médecine d'urgence (Émond), Faculté de médecine, Université Laval, Québec, Que.; Department of Emergency Medicine (Gosselin), McGill University Health Centre, McGill University; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal; Center for Advanced Research in Sleep Medicine (Lavigne), Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord de-l'Île-de-Montréal); Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM) (Choinière, Boulanger); Département d'anesthésiologie (Choinière), Faculté de médecine, Université de Montréal; Research Centre (Daoust, Paquet, Mac-Thiong, Chauny), Hôpital du Sacré-Coeur (CIUSSS du Nord de-l'Île-de-Montréal), Montréal, Que.
Sophie GosselinDepartment of Emergency Medicine (Daoust, Paquet, Chauny), Research Centre, Hôpital du Sacré-Coeur de Montréal; Faculté de Médecine (Daoust, Mac-Thiong, Chauny), Université de Montréal; Montréal, Que.; Département de médecine sociale et préventive (Moore), Faculté de médecine, Université Laval; Axe de recherche en traumatologie-urgence-soins intensifs du Centre de recherche FRQS du CHU-Québec (Moore); Département de médecine familiale et de médecine d'urgence (Émond), Faculté de médecine, Université Laval, Québec, Que.; Department of Emergency Medicine (Gosselin), McGill University Health Centre, McGill University; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal; Center for Advanced Research in Sleep Medicine (Lavigne), Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord de-l'Île-de-Montréal); Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM) (Choinière, Boulanger); Département d'anesthésiologie (Choinière), Faculté de médecine, Université de Montréal; Research Centre (Daoust, Paquet, Mac-Thiong, Chauny), Hôpital du Sacré-Coeur (CIUSSS du Nord de-l'Île-de-Montréal), Montréal, Que.
Gilles LavigneDepartment of Emergency Medicine (Daoust, Paquet, Chauny), Research Centre, Hôpital du Sacré-Coeur de Montréal; Faculté de Médecine (Daoust, Mac-Thiong, Chauny), Université de Montréal; Montréal, Que.; Département de médecine sociale et préventive (Moore), Faculté de médecine, Université Laval; Axe de recherche en traumatologie-urgence-soins intensifs du Centre de recherche FRQS du CHU-Québec (Moore); Département de médecine familiale et de médecine d'urgence (Émond), Faculté de médecine, Université Laval, Québec, Que.; Department of Emergency Medicine (Gosselin), McGill University Health Centre, McGill University; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal; Center for Advanced Research in Sleep Medicine (Lavigne), Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord de-l'Île-de-Montréal); Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM) (Choinière, Boulanger); Département d'anesthésiologie (Choinière), Faculté de médecine, Université de Montréal; Research Centre (Daoust, Paquet, Mac-Thiong, Chauny), Hôpital du Sacré-Coeur (CIUSSS du Nord de-l'Île-de-Montréal), Montréal, Que.
Manon ChoinièreDepartment of Emergency Medicine (Daoust, Paquet, Chauny), Research Centre, Hôpital du Sacré-Coeur de Montréal; Faculté de Médecine (Daoust, Mac-Thiong, Chauny), Université de Montréal; Montréal, Que.; Département de médecine sociale et préventive (Moore), Faculté de médecine, Université Laval; Axe de recherche en traumatologie-urgence-soins intensifs du Centre de recherche FRQS du CHU-Québec (Moore); Département de médecine familiale et de médecine d'urgence (Émond), Faculté de médecine, Université Laval, Québec, Que.; Department of Emergency Medicine (Gosselin), McGill University Health Centre, McGill University; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal; Center for Advanced Research in Sleep Medicine (Lavigne), Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord de-l'Île-de-Montréal); Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM) (Choinière, Boulanger); Département d'anesthésiologie (Choinière), Faculté de médecine, Université de Montréal; Research Centre (Daoust, Paquet, Mac-Thiong, Chauny), Hôpital du Sacré-Coeur (CIUSSS du Nord de-l'Île-de-Montréal), Montréal, Que.
Aline BoulangerDepartment of Emergency Medicine (Daoust, Paquet, Chauny), Research Centre, Hôpital du Sacré-Coeur de Montréal; Faculté de Médecine (Daoust, Mac-Thiong, Chauny), Université de Montréal; Montréal, Que.; Département de médecine sociale et préventive (Moore), Faculté de médecine, Université Laval; Axe de recherche en traumatologie-urgence-soins intensifs du Centre de recherche FRQS du CHU-Québec (Moore); Département de médecine familiale et de médecine d'urgence (Émond), Faculté de médecine, Université Laval, Québec, Que.; Department of Emergency Medicine (Gosselin), McGill University Health Centre, McGill University; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal; Center for Advanced Research in Sleep Medicine (Lavigne), Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord de-l'Île-de-Montréal); Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM) (Choinière, Boulanger); Département d'anesthésiologie (Choinière), Faculté de médecine, Université de Montréal; Research Centre (Daoust, Paquet, Mac-Thiong, Chauny), Hôpital du Sacré-Coeur (CIUSSS du Nord de-l'Île-de-Montréal), Montréal, Que.
Jean-Marc Mac-ThiongDepartment of Emergency Medicine (Daoust, Paquet, Chauny), Research Centre, Hôpital du Sacré-Coeur de Montréal; Faculté de Médecine (Daoust, Mac-Thiong, Chauny), Université de Montréal; Montréal, Que.; Département de médecine sociale et préventive (Moore), Faculté de médecine, Université Laval; Axe de recherche en traumatologie-urgence-soins intensifs du Centre de recherche FRQS du CHU-Québec (Moore); Département de médecine familiale et de médecine d'urgence (Émond), Faculté de médecine, Université Laval, Québec, Que.; Department of Emergency Medicine (Gosselin), McGill University Health Centre, McGill University; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal; Center for Advanced Research in Sleep Medicine (Lavigne), Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord de-l'Île-de-Montréal); Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM) (Choinière, Boulanger); Département d'anesthésiologie (Choinière), Faculté de médecine, Université de Montréal; Research Centre (Daoust, Paquet, Mac-Thiong, Chauny), Hôpital du Sacré-Coeur (CIUSSS du Nord de-l'Île-de-Montréal), Montréal, Que.
Jean-Marc ChaunyDepartment of Emergency Medicine (Daoust, Paquet, Chauny), Research Centre, Hôpital du Sacré-Coeur de Montréal; Faculté de Médecine (Daoust, Mac-Thiong, Chauny), Université de Montréal; Montréal, Que.; Département de médecine sociale et préventive (Moore), Faculté de médecine, Université Laval; Axe de recherche en traumatologie-urgence-soins intensifs du Centre de recherche FRQS du CHU-Québec (Moore); Département de médecine familiale et de médecine d'urgence (Émond), Faculté de médecine, Université Laval, Québec, Que.; Department of Emergency Medicine (Gosselin), McGill University Health Centre, McGill University; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal; Center for Advanced Research in Sleep Medicine (Lavigne), Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord de-l'Île-de-Montréal); Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM) (Choinière, Boulanger); Département d'anesthésiologie (Choinière), Faculté de médecine, Université de Montréal; Research Centre (Daoust, Paquet, Mac-Thiong, Chauny), Hôpital du Sacré-Coeur (CIUSSS du Nord de-l'Île-de-Montréal), Montréal, Que.
Hôpital du Sacré-Cœur de Montréal · CA
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEvidence for an association between opioid use and risk of falls or fractures in older adults is inconsistent. We examine the association between recent opioid use and the risk, as well as the clinical outcomes, of fall-related injuries in a large trauma population of older adults.
methodsIn a retrospective, observational, multicentre cohort study conducted on registry data, we included all patients aged 65 years and older who were admitted (hospital stay > 2 d) for injury in 57 trauma centres in the province of Quebec, Canada, between 2004 and 2014. We looked at opioid prescriptions filled in the 2 weeks preceding the trauma in patients who sustained a fall, compared with those who sustained an injury through another mechanism.
resultsA total of 67 929 patients were retained for analysis. Mean age was 80.9 (± 8.0) years and 69% were women. The percentage of patients who had filled an opioid prescription in the 2 weeks preceding an injury was 4.9% (95% confidence interval [CI] 4.7%-5.1%) for patients who had had a fall, compared with 1.5% (95% CI 1.2%-1.8%) for those who had had an injury through another mechanism. After we controlled for confounding variables, patients who had filled an opioid prescription within 2 weeks before injury were 2.4 times more likely to have a fall rather than any other type of injury. For patients who had a fall-related injury, those who used opioids were at increased risk of in-hospital death (odds ratio 1.58; 95% CI 1.34-1.86).
interpretationRecent opioid use is associated with an increased risk of fall and an increased likelihood of death in older adults.
Indexed as
Accidental FallsAgedAged, 80 and overAnalgesics, OpioidFemaleFractures, BoneHumansLength of StayMaleQuebecRetrospective StudiesRisk FactorsTrauma CentersAnalgesics, Opioid
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