Evidence map›Paper›PMID 29685888›Full record

ArticleThe Journal of biological chemistry2018

The

Yuzhou Tang, Fabian B Romano, Mariana Breña, Alejandro P Heuck

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Monosodium Glutamate InhibitsMicroorganisms · 2026
    Article
  4. Article
  5. Article
  6. Human Saposin B Ligand Binding and Presentation to α-Galactosidase A.bioRxiv : the preprint server for biology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Immunopotentiating properties of chimeric OprF-OprI-PopB protein againstIranian journal of basic medical sciences · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. The type III secretion system needle, tip, and translocon.Protein science : a publication of the Protein Society · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yuzhou TangFrom the Program in Molecular and Cellular Biology and.
Fabian B RomanoFrom the Program in Molecular and Cellular Biology and.
Mariana BreñaFrom the Program in Molecular and Cellular Biology and.
Alejandro P HeuckFrom the Program in Molecular and Cellular Biology and heuck@umass.edu.ORCID 0000-0002-7786-3109
University of Massachusetts Amherst · US

Funding

CHEMISTRY-BIOLOGY INTERFACE PREDOCTORAL TRAINING GRANTST32GM008515 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI THOMPSON, LYNMARIE K. · 1995 to 2020
$4.3M
Molecular Mechanism of Translocon Assembly into Cell Plasma MembranesR01GM097414 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI HEUCK, ALEJANDRO PABLO · 2012 to 2016
$1.5M
NIGMS NIH HHS R01 GM097414NIGMS NIH HHS T32 GM008515
6 · The paper itself

Abstract

Many Gram-negative bacterial pathogens use a type III secretion system to infect eukaryotic cells. The injection of bacterial toxins or protein effectors via this system is accomplished through a plasma membrane channel formed by two bacterial proteins, termed translocators, whose assembly and membrane-insertion mechanisms are currently unclear. Here, using purified proteins we demonstrate that the translocators PopB and PopD in

Indexed as

Host-Pathogen InteractionsAntigens, BacterialBacterial ProteinsCell MembraneHeLa CellsHumansHydrophobic and Hydrophilic InteractionsProtein MultimerizationPseudomonas aeruginosaPseudomonas InfectionsType III Secretion SystemsAntigens, BacterialBacterial ProteinsPopB protein, Pseudomonas aeruginosaType III Secretion Systemsfluorescenceinfectionmembrane proteinmembrane transportPerfringolysin OPopBPopDprotein assemblyprotein translocationPseudomonas aeruginosa (P. aeruginosa)quenchingtranslocationtranslocontype III secretion system (T3SS)

Identifiers

PMID29685888
PMCPMC5995524
OpenAlexW2799696510

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.