Evidence map›Paper›PMID 29685701›Full record

ArticleClinical lung cancer2018

Cost Analysis of PET/CT Versus CT as Surveillance for Stage III Non-Small-Cell Lung Cancer After Definitive Radiation Therapy.

Charissa R Kim, Bumyang Kim, Matthew S Ning, Jay P Reddy, Zhongxing Liao, Chad Tang, James W Welsh, Frank E Mott, Ya-Chen Tina Shih, Daniel R Gomez

Abstract read
In one paragraph

Article in Clinical lung cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Charissa R KimDepartment of Genetics, The University of Texas M.D. Anderson Cancer Center, Houston, TX.
Bumyang KimDepartment of Health Services Research, The University of Texas M.D. Anderson Cancer Center, Houston, TX.
Matthew S NingDepartment of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX.
Jay P ReddyDepartment of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX.
Zhongxing LiaoDepartment of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX.
Chad TangDepartment of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX.
James W WelshDepartment of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX.
Frank E MottDepartment of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX.
Ya-Chen Tina ShihDepartment of Health Services Research, The University of Texas M.D. Anderson Cancer Center, Houston, TX.
Daniel R GomezDepartment of Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX. Electronic address: dgomez@mdanderson.org.
The University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Technology Diffusion in Cancer: Geographic Variations, Facilitators, Outcomes, and CostsR01CA207216 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SHIH, YA-CHEN TINA · 2016 to 2020
$1.6M
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA207216
6 · The paper itself

Abstract

introductionA previous study showed that use of positron emission tomography (PET)/computed tomography (CT) for surveillance after treatment of non-small-cell lung cancer (NSCLC) does not yield a detection or survival benefit over the use of chest CT. However, PET/CT remains a common method of follow-up imaging. Here we estimated and compared the costs of PET/CT versus CT for surveillance of patients with stage III NSCLC and identified patient and provider demographic characteristics associated with preference for use of PET/CT. PATIENTS AND

methodsWe reviewed 178 patients with stage III NSCLC who had received ≥ 1 PET/CT scan within 6 months of completing radiotherapy (n = 89) or had received CT after radiotherapy (n = 89) from 2000 to 2011. Costs were measured according to Medicare payments converted from institutional billing records. Total and imaging costs were analyzed at 6, 12, 18, and 24 months after the end of treatment. Patient and provider demographic characteristics were also evaluated for potential associations with PET/CT use.

resultsTotal costs in the PET/CT group were higher during the first 18 months after treatment (P = .002 at 6 months, P = .019 at 12 months, and P = .018 at 18 months) but was marginally significant (P = .05) at 24 months. In univariate analysis of demographic variables, patients who lived in a state different from the treatment center might have been more likely to receive PET/CT (odds ratio [OR], 1.76; P = .051). In multivariate analysis, patients treated in 2007 to 2010 (OR, 29.9; P < .001) or 2003 to 2006 (OR, 11.6; P = .002) were more likely to receive PET/CT than patients treated in 1999 to 2002. In addition, radiation oncologists with > 10 years of experience were more likely to use PET/CT than those with less experience, although this result might be confounded by the small number of providers.

conclusionUse of PET/CT was associated with higher costs for 18 months after treatment, but the difference was at the borderline of statistical significance at 24 months.

Indexed as

AdultAgedCarcinoma, Non-Small-Cell LungCosts and Cost AnalysisFemaleHumansLung NeoplasmsMaleMiddle AgedNeoplasm Recurrence, LocalPositron Emission Tomography Computed TomographyTomography, X-Ray ComputedBenefitClinical costNon–small-cell lung carcinomaRadiotherapyRecurrence

Identifiers

PMID29685701
PMCPMC6463892
OpenAlexW2794333902

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.