Evidence map›Paper›PMID 29684698›Full record

ArticleJournal of inorganic biochemistry2018

Biophysical characterization of Aptenodytes forsteri cytochrome P450 aromatase.

Francisco Zarate-Perez, Jesús B Velázquez-Fernández, Gareth K Jennings, Lisa S Shock, Charles E Lyons, John C Hackett

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of inorganic biochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Francisco Zarate-PerezDepartment of Physiology and Biophysics, the Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond, VA 23298-0035, United States.
Jesús B Velázquez-FernándezDepartment of Physiology and Biophysics, the Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond, VA 23298-0035, United States.
Gareth K JenningsDepartment of Physiology and Biophysics, the Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond, VA 23298-0035, United States.
Lisa S ShockDepartment of Physiology and Biophysics, the Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond, VA 23298-0035, United States; Department of Microbiology and Immunology, the Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond, VA 23298-0035, United States.
Charles E LyonsDepartment of Physiology and Biophysics, the Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond, VA 23298-0035, United States.
John C HackettDepartment of Physiology and Biophysics, the Massey Cancer Center, Virginia Commonwealth University School of Medicine, Richmond, VA 23298-0035, United States. Electronic address: john.hackett@vcuhealth.org.
Virginia Commonwealth University · US

Funding

Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Keri R Maher · 1985 to 2026
$51.0M
Computational and Vibrational Probes of CYP3A4 Solution DynamicsR01GM114168 · NIGMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI HACKETT, JOHN C · 2015 to 2018
$1.3M
NCI NIH HHS P30 CA016059NIGMS NIH HHS R01 GM114168
6 · The paper itself

Abstract

Cytochrome P450 19 (CYP19, aromatase) catalyzes the conversion of androgens to estrogens in a sequence of three reactions that each depend on NADPH and O

Indexed as

AnastrozoleAndrostenedioneAromataseCytochrome P-450 Enzyme SystemSpectrum Analysis, RamanTestosterone19-hydroxy-4-androstene-3,17-dioneAnastrozoleAndrostenedioneAromataseCytochrome P-450 Enzyme SystemTestosteroneAptenodytes forsteriAromataseCytochrome P450Enzyme kineticsResonance Raman spectroscopyStopped-flow kinetics

Identifiers

PMID29684698
PMCPMC5964043
OpenAlexW2796321917

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.