Evidence map›Paper›PMID 29684316›Full record

Trial reportChest2018

CPAP Adherence Predictors in a Randomized Trial of Moderate-to-Severe OSA Enriched With Women and Minorities.

Anna M May, Tarek Gharibeh, Lu Wang, Amanda Hurley, Harneet Walia, Kingman P Strohl, Reena Mehra

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Chest, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00607893 (Oxidative Stress in Sleep Apnea and Cardiac Disease), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00607893 nacompletednot on this map

Oxidative Stress in Sleep Apnea and Cardiac Disease

TypeinterventionalSponsorCase Western Reserve UniversityRan2006 to 2011Enrolled153ConditionsSleep Apnea Syndromes, Oxidative Stress, Cardiovascular DiseasesArmsContinuous Positive Airway Pressure (CPAP), Sham CPAP
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The impact of obstructive sleep apnea treatment on microvascular complications in patients with type 2 diabetes: a feasibility randomized controlled trial.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Trial
  3. Trial
  4. Impact of patient and family engagement in improving continuous positive airway pressure adherence in patients with obstructive sleep apnea: a randomized controlled trial.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Trial
  5. Trial
  6. Effect of cloud-based sleep coaches on positive airway pressure adherence.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
    Trial
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Predictors for short-term and long-term automatic PAP compliance.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
  17. Review
  18. Review
  19. Adherence Index: sleep depth and nocturnal hypoventilation predict long-term adherence with positive airway pressure therapy in severe obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anna M MayDivision of Pulmonary, Critical Care, and Sleep Medicine, University Hospitals Case Medical Center, Cleveland, Case Western Reserve University, Cleveland, OH; Division of Pulmonary, Critical Care, and Sleep Medicine, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH. Electronic address: drannamay@gmail.com.
Tarek GharibehDivision of Pulmonary, Critical Care, and Sleep Medicine, University Hospitals Ahuja Medical Center, Cleveland, OH.
Lu WangDepartment of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH.
Amanda HurleyIndiana Wesleyan University School of Nursing, Marion, IN.
Harneet WaliaSleep Disorders Center, Neurological Institute, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.
Kingman P StrohlDivision of Pulmonary, Critical Care, and Sleep Medicine, University Hospitals Case Medical Center, Cleveland, Case Western Reserve University, Cleveland, OH; Division of Pulmonary, Critical Care, and Sleep Medicine, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH.
Reena MehraSleep Disorders Center, Neurological Institute, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024989 · NCRR · CASE WESTERN RESERVE UNIVERSITY · PI DAVIS, PAMELA B · 2007 to 2011
$53.7M
SLEEP MEDICINE NEUROBIOLOGY AND EPIDEMIOLOGYT32HL007913 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI STROHL, KINGMAN PERKINS · 1999 to 2020
$3.2M
Oxidative Stress in Sleep Apnea and Cardiac DiseaseK23HL079114 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI MEHRA, REENA · 2006 to 2010
$645k
NCRR NIH HHS L30 RR020489NCRR NIH HHS UL1 RR024989NHLBI NIH HHS K23 HL079114NHLBI NIH HHS T32 HL007913
6 · The paper itself

Abstract

backgroundSuboptimal CPAP adherence in OSA clinical trials involving predominantly white men limits interpretability and generalizability. We examined predictors of CPAP adherence in a clinical trial enriched with minorities.

methodsThe Sleep Apnea Stress Study-a randomized, double-blind, sham-controlled trial of patients with moderate-to-severe OSA-included participants with complete 8-week adherence data (n = 138). Overnight 14-channel polysomnography, anthropometry, socioeconomic status, mood questionnaires, and week 1 CPAP adherence were analyzed via adjusted linear models relative to CPAP adherence (average minutes per night usage).

resultsOverall, age was 51 ± 12 years, 55% of the patients were male, 55% were white, BMI was 36.7 ± 7.7 kg/m

conclusionsIn this trial with near-even sex distribution and high ethnic minority representation, we identified CPAP assignment, increasing age, and early adherence to be associated with improved adherence in addition to sex-specific and race-specific adherence differences. These results can inform targeted clinical trial adherence optimization strategies. TRIAL REGISTRY: ClinicalTrials.gov; No.: NCT00607893; URL: www.clinicaltrials.gov.

Indexed as

AdultAgedAnthropometryContinuous Positive Airway PressureDouble-Blind MethodFemaleHumansMaleMiddle AgedMinority GroupsPatient CompliancePolysomnographyPsychiatric Status Rating ScalesSocial Classadherenceclinical trials researchCPAPOSA

Identifiers

PMID29684316
PMCPMC6130325

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.