ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2018
Non-invasive epicardial and endocardial electrocardiographic imaging for scar-related ventricular tachycardia.
Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 32 citations in OpenAlex.
- Computer-aided characterization of the arrhythmogenic substrate after myocardial infarction.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Review
- Volumetric non-invasive cardiac mapping for accessible global arrhythmia characterization.Communications medicine · 2026Article
- Noninvasive Cardiac Electrical Activity Mapping Systems: Current Available Options.Reviews in cardiovascular medicine · 2025Review
- Artificial intelligence-based accurate myocardial infarction mapping using 12-lead electrocardiography.European heart journal. Digital health · 2025Article
- A Novel 3D Camera-Based ECG-Imaging System for Electrode Position Discovery and Heart-Torso Registration.IEEE journal of biomedical and health informatics · 2025Article
- Preprocedural imaging guiding ventricular tachycardia ablation in structural heart disease.Journal of arrhythmia · 2025Article
- Electrocardiographic imaging metrics to predict the risk of arrhythmia in patients with ischemic cardiomyopathy.Journal of arrhythmia · 2025Article
- Understanding the Utility of Endocardial Electrocardiographic Imaging in Epi-Endocardial Mapping of 3D Reentrant Circuits.medRxiv : the preprint server for health sciences · 2024Article
- Innovations in ventricular tachycardia ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023Review
- Basis and applicability of noninvasive inverse electrocardiography: a comparison between cardiac source models.Frontiers in physiology · 2023Review
- Ajmaline-Induced Abnormalities in Brugada Syndrome: Evaluation With ECG Imaging.Journal of the American Heart Association · 2022Article
- Electrocardiographic imaging for cardiac arrhythmias and resynchronization therapy.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2020Article
- How personalized heart modeling can help treatment of lethal arrhythmias: A focus on ventricular tachycardia ablation strategies in post-infarction patients.Wiley interdisciplinary reviews. Systems biology and medicine · 2020Review
- Embedding high-dimensional Bayesian optimization via generative modeling: Parameter personalization of cardiac electrophysiological models.Medical image analysis · 2020Article
- Mapping Ventricular Tachycardia With Electrocardiographic Imaging.Circulation. Arrhythmia and electrophysiology · 2020Article
- Mechanisms of Arrhythmogenicity in Hypertrophic Cardiomyopathy: Insight From Non-invasive Electrocardiographic Imaging.Frontiers in physiology · 2020Article
- Validation and Opportunities of Electrocardiographic Imaging: From Technical Achievements to Clinical Applications.Frontiers in physiology · 2018Review
- Combining endocardial mapping and electrocardiographic imaging (ECGI) for improving PVC localization: A feasibility study.Journal of electrocardiologyArticle
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Aims: Contact mapping is currently used to guide catheter ablation of scar-related ventricular tachycardia (VT) but usually provides incomplete assessment of 3D re-entry circuits and their arrhythmogenic substrates. This study investigates the feasibility of non-invasive electrocardiographic imaging (ECGi) in mapping scar substrates and re-entry circuits throughout the epicardium and endocardium. Methods and results: Four patients undergoing endocardial and epicardial mapping and ablation of scar-related VT had computed tomography scans and a 120-lead electrocardiograms, which were used to compute patient-specific ventricular epicardial and endocardial unipolar electrograms (CEGMs). Native-rhythm CEGMs were used to identify sites of myocardial scar and signal fractionation. Computed electrograms of induced VT were used to localize re-entrant circuits and exit sites. Results were compared to in vivo contact mapping data and epicardium-based ECGi solutions. During native rhythm, an average of 493 ± 18 CEGMs were analysed on each patient. Identified regions of scar and fractionation comprised, respectively, 25 ± 4% and 2 ± 1% of the ventricular surface area. Using a linear mixed-effects model grouped at the level of an individual patient, CEGM voltage and duration were significantly associated with contact bipolar voltage. During induced VT, the inclusion of endocardial layer in ECGi made it possible to identify two epicardial vs. three endocardial VT exit sites among five reconstructed re-entry circuits. Conclusion: Electrocardiographic imaging may be used to reveal sites of signal fractionation and to map short-lived VT circuits. Its capacity to map throughout epicardial and endocardial layers may improve the delineation of 3D re-entry circuits and their arrhythmogenic substrates.
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