ReviewBritish medical bulletin2018
Maternal vitamin D supplementation during pregnancy.
Review in British medical bulletin, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 4 syntheses or guidelines pooled it, 109 citations in OpenAlex.
- Association of Pregnancy Diet with Metabolic Adverse Outcomes in Pregnant Women and Their Children: A Systematic Review and Meta-Analysis.Annals of nutrition & metabolism · 2025Pooled it
- Associations of Prenatal Vitamin D status with Oral Health in Offspring: A Systematic Review.Oral health & preventive dentistry · 2022Pooled it
- Pooled it
- Effect of micronutrient supplements on low-risk pregnancies in high-income countries: a systematic quantitative literature review.Public health nutrition · 2020Pooled it
- Trial
- The Effect of Vitamin D Supplementation in Pregnant Women with Overweight and Obesity: A Randomised Controlled Trial.Nutrients · 2023Trial
- Maternal antenatal vitamin D supplementation and offspring risk of atopic eczema in the first 4 years of life: evidence from a randomized controlled trial.The British journal of dermatology · 2022Trial
- Efficacy of two different doses of oral vitamin D supplementation on inflammatory biomarkers and maternal and neonatal outcomes.Maternal & child nutrition · 2019Trial
- Optimisation of Micronutrient Supplementation During Pregnancy: Interactions Between Bioactive Compounds, Their Impact on Health, and Regulatory Considerations.Biomolecules · 2026Review
- Predictors of Maternal Vitamin D Deficiency and Associated Adverse Neonatal Outcomes in Eastern Uganda: A Cross-Sectional Study.Health science reports · 2026Article
- Serum Vitamin D Levels in Pregnant Women: The Role of Supplementation on Preterm Infant Outcomes.Journal of pregnancy · 2026Article
- Beyond deficiency prevention: meteorological determinants and nonlinear associations of maternal vitamins D, A, and E with perinatal outcomes in 10,824 Chinese pregnancies.Frontiers in nutrition · 2026Article
- Relationship between group B Streptococcal rectovaginal colonization and Vitamin D deficiency in pregnant women.BMC pregnancy and childbirth · 2025Article
- Article
- Vitamin D Knowledge, Attitudes, Practices and Serum Concentration Among Pregnant Women Attending a Malaysian Tertiary Hospital.Food science & nutrition · 2025Article
- Could serum Vitamin-D be an indicator of the onset of membrane rupture?Pakistan journal of medical sciences · 2025Article
- Assessment of the maternal key micronutrient supply and its correlation with cord blood parameters in twin pregnancies.Frontiers in public health · 2025Article
- Article
- Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Introduction: Maternal vitamin D status in pregnancy has been linked to many health outcomes in mother and offspring. A wealth of observational studies have reported on both obstetric outcomes and complications, including pre-eclampsia, gestational diabetes, mode and timing of delivery. Many foetal and childhood outcomes are also linked to vitamin D status, including measures of foetal size, body composition and skeletal mineralization, in addition to later childhood outcomes, such as asthma. Sources of data: Synthesis of systematic and narrative reviews. Areas of agreement and controversy: The findings are generally inconsistent in most areas, and, at present, there is a lack of data from high-quality intervention studies to confirm a causal role for vitamin D in these outcomes. In most areas, the evidence tends towards maternal vitamin D being of overall benefit, but often does not reach statistical significance in meta-analyses. Growing points and areas timely for developing research: The most conclusive evidence is in the role of maternal vitamin D supplementation in the prevention of neonatal hypocalcaemia; as a consequence the UK department of health recommends that pregnant women take 400 IU vitamin D daily. High-quality randomized placebo-controlled trials, such as the UK-based MAVIDOS trial, will inform the potential efficacy and safety of vitamin D supplementation in pregnancy across a variety of outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.