ArticlePLoS neglected tropical diseases2018
Cryosurgery for the treatment of cutaneous sporotrichosis in four pregnant women.
Article in PLoS neglected tropical diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- The Current Landscape of Repurposed Drugs for Fungal Neglected Tropical Diseases.Current fungal infection reports · 2025Article
- In vitro effects of the new antifungal compound manogepix (APX001) against the three most clinically relevant species of Sporothrix.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Cryotherapy for treatment of sporotrichosis-rapid cure with adjuvant cryotherapy: case report.Journal of medical case reports · 2025Article
- Sporotrichosis: an overview of the neglected disease reported worldwide in the last five years.Revista da Sociedade Brasileira de Medicina Tropical · 2025Review
- Sporotrichosis during pregnancy: A retrospective study of 58 cases in a reference center from 1998 to 2023.PLoS neglected tropical diseases · 2024Article
- Whole transcriptome sequencing for revealing the pathogenesis of sporotrichosis caused by Sporothrix globosa.Scientific reports · 2024Article
- The State of the Art in Transcriptomics and Proteomics of Clinically RelevantJournal of fungi (Basel, Switzerland) · 2023Review
- Sporotrichosis in the nasal mucosa: A single-center retrospective study of 37 cases from 1998 to 2020.PLoS neglected tropical diseases · 2023Article
- Severe form of lymphocutaneous sporotrichosis: a case report.Revista do Instituto de Medicina Tropical de Sao Paulo · 2023Article
- Sporotrichosis: A Review of a Neglected Disease in the Last 50 Years in Brazil.Microorganisms · 2022Review
- Current Progress on Epidemiology, Diagnosis, and Treatment of Sporotrichosis and Their Future Trends.Journal of fungi (Basel, Switzerland) · 2022Review
- Epidemiology of Clinical Sporotrichosis in the Americas in the Last Ten Years.Journal of fungi (Basel, Switzerland) · 2022Review
- In vitro activity of Schinus terebinthifolius extract and fractions against Sporothrix brasiliensis.Memorias do Instituto Oswaldo Cruz · 2022Article
- Review
- Subcutaneous Mycoses in Travelers.Current tropical medicine reports · 2020Article
- A One Health Approach to CombattingJournal of fungi (Basel, Switzerland) · 2020Review
- The threat of emerging and re-emerging pathogenic Sporothrix species.Mycopathologia · 2020Review
- Nodular Lymphangitis (Sporotrichoid Lymphocutaneous Infections). Clues to Differential Diagnosis.Journal of fungi (Basel, Switzerland) · 2018Review
- Human sporotrichosis: recommendations from the Brazilian Society of Dermatology for the clinical, diagnostic and therapeutic management.Anais brasileiros de dermatologiaArticle
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPregnant women with sporotrichosis should not receive systemic antifungal therapy except in severe cases when amphotericin B is recommended. Thermotherapy is the most reported treatment described in this group of patients. It entails weeks of daily self-application of heat to the lesions, requires that the patient faithfully apply it, and it could cause skin burns. Cryosurgery is a useful therapeutic tool for many cutaneous infectious diseases, safe for pregnant women, but not well evaluated for sporotrichosis treatment in this group. METHODOLOGY: The authors conducted a retrospective study describing epidemiological, clinical, and therapeutic data related to four pregnant patients with sporotrichosis treated with cryosurgery. The authors reviewed the clinical records of four pregnant patients diagnosed with cutaneous sporotrichosis and treated with cryosurgery. The sessions were carried out monthly up to clinical cure. Molecular identification of the Sporothrix species was performed in two cases using T3B PCR fingerprinting assays. PRINCIPAL
findingsAll patients were in the second trimester of pregnancy and their age ranged from 18 to 34 years. With regard to clinical presentation, two patients had lymphocutaneous and two had the fixed form. S. brasiliensis was identified in two cases as the causative agent. Cryosurgery was well tolerated and the number of sessions ranged from 1 to 3. All the patients reached a complete clinical cure.
conclusionsCryosurgery was a safe, easy to perform and well tolerated method, and therefore it is suggested to be a suitable option for the treatment of cutaneous sporotrichosis in pregnant women.
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