Evidence map›Paper›PMID 29683463›Full record

ArticleJournal of visualized experiments : JoVE2018

A Closed-chest Model to Induce Transverse Aortic Constriction in Mice.

Lars Eichhorn, Christina Katharina Weisheit, Christopher Gestrich, Konrad Peukert, Georg Daniel Duerr, Muhammad Ajmal Ayub, Felix Erdfelder, Florian Stöckigt

Open access · bronzeAbstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  8. Calpains as Potential Therapeutic Targets for Myocardial Hypertrophy.International journal of molecular sciences · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Lars EichhornDepartment of Anaesthesiology, University Hospital Bonn; Lars.Eichhorn@ukbonn.de.
Christina Katharina WeisheitDepartment of Anaesthesiology, University Hospital Bonn.
Christopher GestrichDepartment of Cardiac Surgery, University Hospital Bonn.
Konrad PeukertDepartment of Anaesthesiology, University Hospital Bonn.
Georg Daniel DuerrDepartment of Cardiac Surgery, University Hospital Bonn.
Muhammad Ajmal AyubInstitute of Physiology 2, University of Bonn.
Felix ErdfelderDepartment of Anaesthesiology, University Hospital Bonn.
Florian StöckigtDepartment of Medicine - Cardiology, University Hospital Bonn.
University Hospital Bonn · DECzech Academy of Sciences, Institute of Physiology · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research on cardiac hypertrophy and heart failure is frequently based on pressure overload mouse models induced by TAC. The standard procedure is to perform a partial thoracotomy to visualize the transverse aortic arch. However, the surgical trauma caused by the thoracotomy in open-chest models changes the respiratory physiology as the ribs are dissected and left unattached after chest closure. To prevent this, we established a minimally invasive, closed chest approach via lateral thoracotomy. Herein we approach the aortic arch via the 2

Indexed as

AnimalsAorta, ThoracicConstrictionDisease Models, AnimalMaleMiceMice, Inbred C57BLThoracotomy

Identifiers

PMID29683463
PMCPMC5933408
OpenAlexW2795623820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.