Evidence map›Paper›PMID 29683114›Full record

ArticleOncology nursing forum2018

Trajectories of Cognitive Function and Associated Phenotypic and Genotypic Factors in Breast Cancer.

Catherine M Bender, John D Merriman, Susan M Sereika, Amanda L Gentry, Frances E Casillo, Theresa A Koleck, Margaret Q Rosenzweig, Adam M Brufsky, Priscilla McAuliffe, Yehui Zhu and 1 more

Abstract readComparative Study
In one paragraph

Article in Oncology nursing forum, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. Role function in postmenopausal women during aromatase inhibitor therapy for breast cancer.Journal of cancer survivorship : research and practice · 2026
    Article
  3. Review
  4. Observational
  5. Article
  6. Article
  7. Psychoneurological symptom cluster trajectories in individuals treated for early-stage breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  8. Genetic variability of oxidative stress and DNA repair genes associated with pre-treatment cancer-related fatigue in women with breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  9. Review
  10. Article
  11. Trajectories of neuropsychological symptom burden in postmenopausal women prescribed anastrozole for early-stage breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  12. Review
  13. Review
  14. Review
  15. Physical activity, cardiorespiratory fitness, and cognitive function in postmenopausal women with breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  16. Review
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Catherine M BenderUniversity of Pittsburgh.
John D MerrimanUniversity of Pittsburgh.
Susan M SereikaAssociate professors School of Nursing, University of Pittsburgh, Pennsylvania.
Amanda L GentryDepartment of Health and Community Systems, School of Medicine.
Frances E CasilloDepartment of Acute and Tertiary Care, Office of Community Partnerships.
Theresa A KoleckColumbia University.
Margaret Q RosenzweigUniversity of Pittsburgh.
Adam M BrufskySchool of Medicine, University of Pittsburgh.
Priscilla McAuliffeUniversity of Pittsburgh.
Yehui ZhuUniversity of Pittsburgh.
Yvette P ConleyUniversity of Pittsburgh.

Funding

Targeting Research and Academic Training of Nurses in GenomicsT32NR009759 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CONLEY, YVETTE P · 2006 to 2025
$4.5M
Long Term Trajectory of Cognitive Function Related to Anastrozole Use in WomenR01CA107408 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BENDER, CATHERINE M. · 2005 to 2015
$3.8M
Mindfulness-Based Stress Reduction to Improve Cognitive Function During Aromatase Inhibitor TherapyR00NR015473 · NINR · NEW YORK UNIVERSITY · PI MERRIMAN, JOHN D. · 2017 to 2019
$731k
Brain Biomarkers of Cognitive and Mood Changes Related to Aromatase Inhibitor UseK99NR015473 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MERRIMAN, JOHN D. · 2015 to 2016
$190k
Cognitive Function and Breast Cancer: Genomics and Disease CharacteristicsF31NR014590 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KOLECK, THERESA ANN · 2013 to 2016
$104k
NCI NIH HHS R01 CA107408NINR NIH HHS F31 NR014590NINR NIH HHS K99 NR015473NINR NIH HHS R00 NR015473NINR NIH HHS T32 NR009759
6 · The paper itself

Abstract

objectivesThis study identified women with unique trajectories of executive function, concentration, and visual working memory before and during adjuvant therapy for breast cancer, and examined phenotypic and genotypic predictors associated with subgroups. SAMPLE &

setting399 postmenopausal women, of whom 288 were women with early-stage breast cancer and 111 were women without breast cancer, matched on age and years of education to the women with breast cancer, and all at an urban cancer center. METHODS & VARIABLES: A repeated-measures design was used; assessments occurred before adjuvant therapy and every six months post-therapy initiation. Group-based trajectory modeling determined subgroups. Multinomial logistic regression identified phenotypic and genotypic characteristics.

resultsThree executive function and concentration trajectory subgroups were identified. IMPLICATIONS FOR NURSING: Advancing age, greater pretherapy fatigue, and poorer pretherapy cognitive function are associated with the low subgroups. DNA repair and oxidative stress mechanisms may be involved in the cognitive changes that women experience.

Indexed as

AdultAgedAge FactorsAnastrozoleAntineoplastic AgentsBreast NeoplasmsChemotherapy, AdjuvantCognitionCognition DisordersCohort StudiesFemaleGenotypeHumansMiddle AgedPhenotypePostmenopauseAnastrozoleAntineoplastic Agentsaromatase inhibitorbreast cancercognitive functiongenotypicphenotypic

Identifiers

PMID29683114
PMCPMC6052441

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.