Evidence map›Paper›PMID 29682999›Full record

ArticleCanadian journal of psychiatry. Revue canadienne de psychiatrie2018

Age of Cannabis Use Onset and Adult Drug Abuse Symptoms: A Prospective Study of Common Risk Factors and Indirect Effects.

Charlie Rioux, Natalie Castellanos-Ryan, Sophie Parent, Frank Vitaro, Richard Ernest Tremblay, Jean Richard Séguin

Registry-linked trialAbstract read
In one paragraph

Article in Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06821035 (Teaching Youth & Families Self-Regulation Skills to Disrupt the Impact of Adverse Childhood Experiences), which is not on this map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06821035 narecruitingnot on this mapstarted 2025, after this paper: background citation

Teaching Youth & Families Self-Regulation Skills to Disrupt the Impact of Adverse Childhood Experiences: Preventing Substance Use in Adversity- Impacted Youth

TypeinterventionalSponsorUniversity of California, IrvineRan2025 to 2028Enrolled210ConditionsAdverse Childhood Experiences, Family FunctioningArmsGarnering Resilience in Traumatized youth and families (GRIT), Digital Citizenship Curriculum (DCC)
3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

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  7. Early substance use and the school environment: A multilevel latent class analysis.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Charlie Rioux1 Department of Psychology, Université de Montréal, Montreal, Quebec, Canada.
Natalie Castellanos-Ryan2 CHU Sainte-Justine Hospital Research Centre, Montreal, Quebec, Canada.
Sophie Parent3 School of Psychoeducation, Université de Montréal, Montreal, Quebec, Canada.
Frank Vitaro2 CHU Sainte-Justine Hospital Research Centre, Montreal, Quebec, Canada.
Richard Ernest Tremblay1 Department of Psychology, Université de Montréal, Montreal, Quebec, Canada.
Jean Richard Séguin2 CHU Sainte-Justine Hospital Research Centre, Montreal, Quebec, Canada.

Funding

CIHR MOP 97910
6 · The paper itself

Abstract

The present study examined 1) whether the associations between cannabis use (CU) age of onset and drug abuse by 28 y remain when controlling for risk factors in childhood, adolescence and early adulthood; and 2) the developmental pathways from early risk factors to drug abuse problems. Participants from a longitudinal sample of boys of low socioeconomic status ( N = 1,030) were followed from 6 to 28 y. We examined the self-reported CU onset between the ages of 13 and 17 y and drug abuse symptoms by 28 y. The odds of developing any drug abuse symptoms by 28 y were reduced by 31% for each year of delayed CU onset (OR = 0.69). Cannabis, alcohol and other drug frequency at 17 y mediated this association. Still, even when taking that frequency of use into account, adolescents who started using cannabis before 15 y were at a higher risk of developing drug abuse symptoms by age 28 y. Significant indirect effects were found from early adolescent delinquency and affiliation with deviant friends to drug abuse symptoms at 28 y through CU age of onset and substance use frequency at 17 y. The results suggest more clearly than before that prevention programs should aim at delaying CU onset to prevent or reduce drug abuse in adulthood. Furthermore, prevention programs targeting delinquency and/or affiliation with deviant friends in childhood or early adolescence could indirectly reduce substance abuse in adulthood without addressing substance use specifically.

Indexed as

AdolescentAdultAge FactorsAge of OnsetCanadaHumansLongitudinal StudiesMaleMarijuana UsePovertyRisk FactorsSocial ClassSubstance-Related DisordersYoung Adultcannabisearly onsetmarijuanasubstance abuse disorder

Identifiers

PMID29682999
PMCPMC6099774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.