Evidence map›Paper›PMID 29682573›Full record

ArticleBioMed research international2018

Antibody-Mediated Osseous Regeneration for Bone Tissue Engineering in Canine Segmental Defects.

A Khojasteh, S Hosseinpour, M M Dehghan, F Mashhadiabbas, M Rezai Rad, S Ansari, S Farzad Mohajeri, H H Zadeh

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. An overview of de novo bone generation in animal models.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

A KhojastehSchool of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-5378-852X
S HosseinpourStudents' Research Committee, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
M M DehghanDepartment of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
F MashhadiabbasOral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
M Rezai RadSchool of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0001-6998-4499
S AnsariUniversity of California, Los Angeles, CA, USA.ORCID 0000-0001-7965-0927
S Farzad MohajeriDepartment of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.ORCID 0000-0003-4694-347X
H H ZadehLaboratory for Immunoregulation and Tissue Engineering (LITE), Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0002-7770-9363
Shahid Beheshti University of Medical Sciences · IRUniversity of Tehran · IRUniversity of California, Los Angeles · USUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among many applications of therapeutic monoclonal antibodies (mAbs), a unique approach for regenerative medicine has entailed antibody-mediated osseous regeneration (AMOR). In an effort to identify a clinically relevant model of craniofacial defect, the present study investigated the efficacy of mAb specific for bone morphogenetic protein- (BMP-) 2 to repair canine segmental mandibular continuity defect model. Accordingly, a 15 mm unilateral segmental defect was created in mandible and fixated with a titanium plate. Anorganic bovine bone mineral with 10% collagen (ABBM-C) was functionalized with 25

Indexed as

AnimalsAntibodies, MonoclonalBone DensityBone Morphogenetic Protein 2Bone RegenerationCollagenDogsHumansMaleMandibleOsteogenesisRecombinant ProteinsTissue EngineeringTissue ScaffoldsTitaniumTransforming Growth Factor betaAntibodies, MonoclonalBone Morphogenetic Protein 2Collagenrecombinant human bone morphogenetic protein-2Recombinant ProteinsTitaniumTransforming Growth Factor beta

Identifiers

PMID29682573
PMCPMC5851338
OpenAlexW2792909332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.