ReviewOncotarget2018
Leptin signaling axis specifically associates with clinical prognosis and is multifunctional in regulating cancer progression.
Review in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 33 citations in OpenAlex.
- Obesity and renal cell carcinoma: Biological mechanisms and perspectives.Seminars in cancer biology · 2023Review
- Association of High Serum Leptin Level with Papillary Thyroid Carcinoma: A Case-Control Study.International journal of hematology-oncology and stem cell research · 2023Article
- The effect of obesity on adipose-derived stromal cells and adipose tissue and their impact on cancer.Cancer metastasis reviews · 2022Review
- Obesity and Thyroid Cancer Risk: An Update.International journal of environmental research and public health · 2022Review
- MCL1 participates in leptin-promoted mitochondrial fusion and contributes to drug resistance in gallbladder cancer.JCI insight · 2021Article
- Article
- Leptin Is Associated with Poor Clinical Outcomes and Promotes Clear Cell Renal Cell Carcinoma Progression.Biomolecules · 2021Article
- Autophagy activation and SREBP-1 induction contribute to fatty acid metabolic reprogramming by leptin in breast cancer cells.Molecular oncology · 2021Article
- Identification of Prognosis-related Hub RNA Binding Proteins Function through Regulating Metabolic Processes in Tongue Cancer.Journal of Cancer · 2021Article
- A Role for Adipocytes and Adipose Stem Cells in the Breast Tumor Microenvironment and Regenerative Medicine.Frontiers in physiology · 2021Review
- Role of Leptin in Inflammation and Vice Versa.International journal of molecular sciences · 2020Review
- Evaluation of the Impact of Cisplatin on Variances in the Expression Pattern of Leptin-Related Genes in Endometrial Cancer Cells.International journal of molecular sciences · 2020Article
- Leptin Signaling Affects Survival and Chemoresistance of Estrogen Receptor Negative Breast Cancer.International journal of molecular sciences · 2020Article
- The role of adipocytokines and their receptors in bladder cancer: expression of adiponectin or leptin is an independent prognosticator.American journal of translational research · 2020Article
- The Impact of Hormonal Imbalances Associated with Obesity on the Incidence of Endometrial Cancer in Postmenopausal Women.Journal of Cancer · 2020Review
- Leptin is a direct transcriptional target of EGR1 in human breast cancer cells.Molecular biology reports · 2019Article
- Expression of Leptin Receptor and Effects of Leptin on Papillary Thyroid Carcinoma Cells.International journal of endocrinology · 2019Article
- Obesity and gastrointestinal cancer: the interrelationship of adipose and tumour microenvironments.Nature reviews. Gastroenterology & hepatology · 2018Review
- Genetics of Severe Obesity.Current diabetes reports · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leptin is a peptide hormone that has been characterized as the ligand of leptin receptor (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.