Evidence map›Paper›PMID 29682210›Full record

ArticleOncotarget2018

Age at menarche and risks of gestational diabetes mellitus: a meta-analysis of prospective studies.

Ya Xiao, Ruixue Chen, Minghao Chen, Anling Luo, Dayi Chen, Qiuer Liang, Yunfei Cai, Liguo Chen, Xiaoshan Zhao

Registry-linked trialOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04251559 (Evaluation of the Relationship Between Age at Menarche and Gestational Diabetes Mellitus), which is not on this map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04251559 nacompletednot on this map

Evaluation of the Relationship Between Age at Menarche and Gestational Diabetes Mellitus

TypeinterventionalSponsorDerince Training and Research HospitalRan2014 to 2019Enrolled374ConditionsDiabetes, Gestational, Menstrual Cycle AbnormalArmsoral glucose loading test
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ya Xiao *School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China.
Ruixue Chen *School of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China.
Minghao Chen *Reproductive center, Guangdong Women and Children Hospital, Guangzhou, 511400, China.
Anling LuoSchool of Basic Medicine, Jinan University, Guangzhou, 510632, China.
Dayi ChenSchool of Basic Medicine, Jinan University, Guangzhou, 510632, China.
Qiuer LiangSchool of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China.
Yunfei CaiSchool of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China.
Liguo ChenSchool of Traditional Chinese Medicine, Jinan University, Guangzhou, 510632, China.
Xiaoshan ZhaoSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, China.
Jinan University · CNGuangdong Province Women and Children Hospital · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccumulating evidence suggests that early menarche is associated with adult obesity, which in turn may increase the risk of insulin resistance and hyperglycemia. However, the relation of menarcheal age with gestational diabetes mellitus (GDM) remains inconsistent across studies. The objective of this meta-analysis was to evaluate the association between age at menarche and GDM risk. MATERIALS AND

methodsWe searched Medline (PubMed), Embase, Web of Knowledge and the Cochrane library through the end of May 2017. We pooled summary relative risks (RR) with 95% confidence intervals (CIs). Stata 12.0 software was used to analyse the data.

resultsFive prospective studies were eligible for inclusion. The results of meta-analysis showed that women in the early menarcheal age group (at < 12 years of age) had a higher risk of GDM compared with those in the "not early" menarcheal age group (at ≥ 13 years of age) (pooled RR = 1.31, 95% CI: 1.05, 1.56) with moderate heterogeneity (I

conclusionsThe findings support an association between earlier age at menarche and increased risk of GDM. Age at menarche may help identify women with increased risk of developing GDM. However, considering the potential limitations in this study, further larger prospective studies are warranted to verify our findings.

Indexed as

gestational diabetesmenarchemenarcheal age

Identifiers

PMID29682210
PMCPMC5908311
OpenAlexW2779495556

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.