Evidence map›Paper›PMID 29682162›Full record

ArticleOxidative medicine and cellular longevity2018

Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting.

Elisabeth Wyart, Simone Reano, Myriam Y Hsu, Dario Livio Longo, Mingchuan Li, Emilio Hirsch, Nicoletta Filigheddu, Alessandra Ghigo, Chiara Riganti, Paolo Ettore Porporato

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. NADNature communications · 2023
    Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. The Atrophic Effect of 1,25(OH)Antioxidants (Basel, Switzerland) · 2021
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Cachexia, a Systemic Disease beyond Muscle Atrophy.International journal of molecular sciences · 2020
    Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Elisabeth WyartDepartment of Molecular Biotechnology and Health Science, Molecular Biotechnology Center, University of Torino, Torino, Italy.
Simone ReanoDepartment of Translational Medicine, Istituto Interuniversitario di Miologia (IIM), University of Piemonte Orientale, Novara, Italy.
Myriam Y HsuDepartment of Molecular Biotechnology and Health Science, Molecular Biotechnology Center, University of Torino, Torino, Italy.
Dario Livio LongoDepartment of Molecular Biotechnology and Health Science, Molecular Imaging Center, University of Torino, Torino, Italy.ORCID 0000-0002-6906-9925
Mingchuan LiDepartment of Molecular Biotechnology and Health Science, Molecular Biotechnology Center, University of Torino, Torino, Italy.ORCID 0000-0001-5185-6392
Emilio HirschDepartment of Molecular Biotechnology and Health Science, Molecular Biotechnology Center, University of Torino, Torino, Italy.ORCID 0000-0002-9073-6024
Nicoletta FilighedduDepartment of Translational Medicine, Istituto Interuniversitario di Miologia (IIM), University of Piemonte Orientale, Novara, Italy.ORCID 0000-0002-3848-611X
Alessandra GhigoDepartment of Molecular Biotechnology and Health Science, Molecular Biotechnology Center, University of Torino, Torino, Italy.ORCID 0000-0002-1193-5296
Chiara RigantiDepartment of Oncology, University of Torino, Torino, Italy.ORCID 0000-0001-9787-4836
Paolo Ettore PorporatoDepartment of Molecular Biotechnology and Health Science, Molecular Biotechnology Center, University of Torino, Torino, Italy.ORCID 0000-0001-8519-1552
University of Turin · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITImaging Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer cachexia is a devastating syndrome occurring in the majority of terminally ill cancer patients. Notably, skeletal muscle atrophy is a consistent feature affecting the quality of life and prognosis. To date, limited therapeutic options are available, and research in the field is hampered by the lack of satisfactory models to study the complexity of wasting in cachexia-inducing tumors, such as pancreatic cancer. Moreover, currently used

Indexed as

AnimalsCachexiaFemaleMiceMice, Inbred C57BLMuscle, SkeletalMuscular AtrophyPancreatic NeoplasmsQuality of Life

Identifiers

PMID29682162
PMCPMC5846462
OpenAlexW2793017307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.