Evidence map›Paper›PMID 29682099›Full record

ReviewDisease markers2018

Markers of Oral Lichen Planus Malignant Transformation.

Mircea Tampa, Constantin Caruntu, Madalina Mitran, Cristina Mitran, Isabela Sarbu, Laura-Cristina Rusu, Clara Matei, Carolina Constantin, Monica Neagu, Simona-Roxana Georgescu

Abstract readReview
In one paragraph

Review in Disease markers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Different Approaches to Oral Lichen Planus Treatment: A Narrative Review.International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mircea Tampa"Victor Babes" Clinical Hospital for Infectious Diseases, 281 Mihai Bravu, 030303 Bucharest, Romania.
Constantin CaruntuDepartment of Physiology, "Carol Davila" University of Medicine and Pharmacy, 8 Eroii Sanitari, 050474 Bucharest, Romania.ORCID 0000-0003-4530-7965
Madalina Mitran"Victor Babes" Clinical Hospital for Infectious Diseases, 281 Mihai Bravu, 030303 Bucharest, Romania.
Cristina Mitran"Victor Babes" Clinical Hospital for Infectious Diseases, 281 Mihai Bravu, 030303 Bucharest, Romania.
Isabela Sarbu"Carol Davila" University of Medicine and Pharmacy, 37 Dionisie Lupu, 020021 Bucharest, Romania.ORCID 0000-0002-2461-1151
Laura-Cristina RusuOral Pathology Department, Faculty of Dentistry, "Victor Babeș" University of Medicine and Pharmacy, 2 Eftimie Murgu, 300041 Timisoara, Romania.ORCID 0000-0001-6375-4705
Clara Matei"Carol Davila" University of Medicine and Pharmacy, 37 Dionisie Lupu, 020021 Bucharest, Romania.
Carolina ConstantinImmunology Department, "Victor Babes" National Institute of Pathology, 99-101 Spl. Independentei, 050096 Bucharest, Romania.ORCID 0000-0002-2870-5497
Monica NeaguImmunology Department, "Victor Babes" National Institute of Pathology, 99-101 Spl. Independentei, 050096 Bucharest, Romania.ORCID 0000-0001-9339-2805
Simona-Roxana Georgescu"Victor Babes" Clinical Hospital for Infectious Diseases, 281 Mihai Bravu, 030303 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral lichen planus (OLP) is a chronic inflammatory disease of unknown etiology with significant impact on patients' quality of life. Malignant transformation into oral squamous cell carcinoma (OSCC) is considered as one of the most serious complications of the disease; nevertheless, controversy still persists. Various factors seem to be involved in the progression of malignant transformation; however, the mechanism of this process is not fully understood yet. Molecular alterations detected in OLP samples might represent useful biomarkers for predicting and monitoring the malignant progression. In this review, we discuss various studies which highlight different molecules as ominous predictors of OLP malignant transformation.

Indexed as

Biomarkers, TumorCarcinoma, Squamous CellHumansLichen Planus, OralMouth NeoplasmsBiomarkers, Tumor

Identifiers

PMID29682099
PMCPMC5846459

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.